Sarafloxacin

Sarafloxacin

Systematic (IUPAC) name
6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	98105-99-8 Y
ATC code	None
PubChem	CID 56208
ChemSpider	50727 Y
UNII	RC3WJ907XY N
ChEMBL	CHEMBL37858 Y
Chemical data
Formula	C20H17F2N3O3
Mol. mass	385.36 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C20H17F2N3O3/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24/h1-4,9-11,23H,5-8H2,(H,27,28) Y Key:XBHBWNFJWIASRO-UHFFFAOYSA-N Y
N(what is this?)  (verify)

Sarafloxacin (INN) is a quinolone antibiotic drug,^[1][2] which was removed from clinical use by the manufacturer (Abbott Laboratories) April 30, 2001.

See also

• Quinolone
• Adverse effects of fluoroquinolones

References

1. ^ "Evaluation of certain veterinary drug residues in food. Fiftieth report of the joint FAO/WHO Expert Committee on Food Additives.". World Health Organ Tech Rep Ser 888: i-vii, 1–95. 1999. PMID 10416362. 
2. ^ Gingerich, WH.; Stehly, GR.; Clark, KJ.; Hayton, WL. (1998). "Crop grouping: a proposal for public aquaculture.". Vet Hum Toxicol 40 Suppl 2: 24–31. PMID 9823579. 

Other/ungrouped

sulfanilamide (Sulfacetamide, Sulfametrole)

Combinations

Trimethoprim/sulfamethoxazole^#

Topoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication)

1st g.	Cinoxacin‡ • Flumequine • Nalidixic acid • Oxolinic acid • Pipemidic acid • Piromidic acid • Rosoxacin
Fluoro- quinolones	2nd g. Ciprofloxacin#  • Enoxacin‡ • Fleroxacin‡ • Lomefloxacin • Nadifloxacin • Ofloxacin • Norfloxacin • Pefloxacin • Rufloxacin 3rd g. Balofloxacin • Grepafloxacin‡ • Levofloxacin • Pazufloxacin • Sparfloxacin‡ • Temafloxacin‡ • Tosufloxacin 4th g. Besifloxacin • Clinafloxacin† • Garenoxacin • Gemifloxacin • Moxifloxacin • Gatifloxacin‡ • Sitafloxacin • Trovafloxacin‡/Alatrofloxacin‡ • Prulifloxacin Vet. Danofloxacin • Difloxacin • Enrofloxacin • Ibafloxacin • Marbofloxacin • Orbifloxacin • Pradofloxacin • Sarafloxacin Related (DG) Aminocoumarins: Novobiocin

Anaerobic DNA
inhibitors

Nitro- imidazole derivatives	Metronidazole#  • Tinidazole • Ornidazole
Nitrofuran derivatives	Nitrofurantoin#  • Furazolidone‡  • Nifurtoinol

RNA synthesis

Rifamycins/ RNA polymerase

Rifampicin • Rifabutin • Rifapentine • Rifaximin

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: BAC bact (clas) gr+f/gr+a(t)/gr-p(c)/gr-o drug(J1p, w, n, m, vacc)