Corticorelin

Corticorelin

Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	79804-71-0
ATC code	V04CD04
PubChem	CID 16132344
UNII	305OE8862Y Y
Chemical data
Formula	C205H339N59O63S
Mol. mass	4670.31 g/mol
Y(what is this?)  (verify)

Corticorelin is a diagnostic agent. It is a corticotropin-releasing hormone.^[1]

The corticorelin stimulation test helps to differentiate between the etiologies of ACTH-dependent hypercortisolism. It is used to evaluate the status of the pituitary-adrenal axis in the differentiation of a pituitary source from an ectopic source of excessive ACTH secretion.

• If corticorelin injection increases plasma levels of ACTH and cortisol, a diagnosis of Cushing's disease is achieved (ACTH of pituitary origin).
• If corticorelin injection leads to little or no response in plasma levels of ACTH or cortisol, a diagnosis of Ectopic ACTH syndrome is confirmed.

See also

• ACTH stimulation test

References

1. ^ Andoh K, Kimura T, Saeki I, et al (June 1994). "General pharmacological properties of the human corticotropin-releasing hormone corticorelin (human)". Arzneimittelforschung 44 (6): 715–26. PMID 8053970. 

Endocrine system

Pituitary function	cortisol: Metyrapone • Corticorelin GH: Sermorelin • Somatorelin
Thyroid function	Thyrotropin • Protirelin
Fertility disturbances	Gonadorelin

Tuberculosis

Tuberculin

Renal function

Inulin and other polyfructosans • Indigo carmine • Phenolsulfonphthalein • Alsactide • Aminohippuric acid