Vesicle-associated membrane protein
- Vesicle-associated membrane protein
Vesicle associated membrane protein (VAMP) family of proteins includes proteins with similar structure.
* VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neuromediator release.
* VAMP3 (known as cellubrevin) is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles.
* VAMP5 and VAMP7 (SYBL1) participate in constitutive exocytosis.
** VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures.
** VAMP7 is found both in secretory granules and endosomes.
* VAMP8 (known as endobrevin) participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells.
*VAMP4 is involved in transport from the Golgi. [cite journal |author=Steegmaier M, Klumperman J, Foletti DL, Yoo JS, Scheller RH |title=Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking |journal=Mol. Biol. Cell |volume=10 |issue=6 |pages=1957–72 |year=1999 |pmid=10359608 |doi=]
References
External links
*
[Category:Proteins
Wikimedia Foundation.
2010.
Look at other dictionaries:
Vesicle-associated membrane protein 8 — (endobrevin), also known as VAMP8, is a human gene.cite web | title = Entrez Gene: VAMP8 vesicle associated membrane protein 8 (endobrevin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=8673| accessdate … Wikipedia
SNARE (protein) — Molecular machinery driving vesicle fusion in neuromediator release. The core SNARE complex is formed by four α helices contributed by synaptobrevin, syntaxin and SNAP 25, synaptotagmin serves as a calcium sensor and regulates intimately the… … Wikipedia
Synaptic vesicle — Neuron A (transmitting) to neuron B (receiving) 1. Mitochondria 2. synaptic vesicle with neurotransmitters 3. Autoreceptor 4. Synapse with neurotransmitter released (serotonin) 5. Postsynaptic receptors activated by neurotransmitter (induction of … Wikipedia
Vesicle (biology and chemistry) — Scheme of a simple vesicle (liposome). A vesicle is a bubble of liquid within another liquid, a supramolecular assembly made up of many different molecules. More technically, a vesicle is a small membrane enclosed sack that can store or transport … Wikipedia
Vesicle (biology) — A vesicle is a small bubble of liquid within a cell. A more formal definition in cell biology, would be that a vesicle is a relatively small, intracellular, membrane enclosed sac that stores or transports substances. Vesicles form naturally… … Wikipedia
Vesicle — In dermatology, a vesicle is a small blister, as on the skin. Vesicles also occur on the mucous membranes, such as the buccal mucosa (the lining of the mouth). Vesicles are less than .5 centimeters in diameter.In anatomy, a vesicle is any small… … Medical dictionary
Cell membrane — Illustration of a Eukaryotic cell membrane The cell membrane or plasma membrane is a biological mem … Wikipedia
G protein-coupled receptor — G protein coupled receptors (GPCRs), also known as seven transmembrane domain receptors, 7TM receptors, heptahelical receptors, and G protein linked receptors (GPLR), comprise a large protein family of transmembrane receptors that sense molecules … Wikipedia
VAMP2 — Vesicle associated membrane protein 2 (synaptobrevin 2), also known as VAMP2, is a human gene.cite web | title = Entrez Gene: VAMP2 vesicle associated membrane protein 2 (synaptobrevin 2)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… … Wikipedia
VAMP3 — Vesicle associated membrane protein 3 (cellubrevin), also known as VAMP3, is a human gene.cite web | title = Entrez Gene: VAMP3 vesicle associated membrane protein 3 (cellubrevin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… … Wikipedia
