KCNU1

protein
name=potassium channel, subfamily U, member 1
caption=


width=
HGNCid=18867
Symbol=KCNU1
AltSymbols=KCa5.1, Slo3, KCNMC1, Kcnma3
EntrezGene=157855
OMIM=
RefSeq=NM_001031836
UniProt=
PDB=
ECnumber=
Chromosome=8
Arm=p
Band=11.2
LocusSupplementaryData=

KCNU1 is a potassium channel.cite journal | author = Schreiber M, Wei A, Yuan A, Gaut J, Saito M, Salkoff L | title = Slo3, a novel pH-sensitive K⁺ channel from mammalian spermatocytes | journal = J. Biol. Chem. | volume = 273 | issue = 6 | pages = 3509–16 | year = 1998 | month = February | pmid = 9452476 | doi = 10.1074/jbc.273.6.3509 | url = | issn = ]

Although this channel is structurally related to the calcium-activated potassium channels, it cannot be classified as such since it is activated by high intracellular pH and relatively insensitive to changes in calcium concentrations.cite journal |author=Wei AD, Gutman GA, Aldrich R, Chandy KG, Grissmer S, Wulff H|title=International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels.|journal= Pharmacol Rev |volume= 57 |issue= 4 |pages= 463–72 |year= 2005 |pmid= 16382103 | doi = 10.1124/pr.57.4.9] cite journal | author = Zhang X, Zeng X, Xia XM, Lingle CJ | title = pH-regulated Slo3 K⁺ channels: properties of unitary currents | journal = J. Gen. Physiol. | volume = 128 | issue = 3 | pages = 301–15 | year = 2006 | month = September | pmid = 16940554 | pmc = 2151565 | doi = 10.1085/jgp.200609551 | url = | issn = ] cite journal | author = Zhang X, Zeng X, Lingle CJ | title = Slo3 K⁺ channels: voltage and pH dependence of macroscopic currents | journal = J. Gen. Physiol. | volume = 128 | issue = 3 | pages = 317–36 | year = 2006 | month = September | pmid = 16940555 | pmc = 2151566 | doi = 10.1085/jgp.200609552 | url = | issn = ]

References