Clostridium difficile toxin A

Clostridium difficile toxin A

Clostridium difficile toxin A is a toxin generated by Clostridium difficile.[1] It is similar to Clostridium difficile Toxin B.

It is usually described as a enterotoxin,[2] but it also has some activity as a cytotoxin.[3]

References

  1. ^ Planche T, Aghaizu A, Holliman R, et al. (December 2008). "Diagnosis of Clostridium difficile infection by toxin detection kits: a systematic review". Lancet Infect Dis 8 (12): 777–84. doi:10.1016/S1473-3099(08)70233-0. PMID 18977696. http://linkinghub.elsevier.com/retrieve/pii/S1473-3099(08)70233-0. 
  2. ^ Peterson LR, Holter JJ, Shanholtzer CJ, Garrett CR, Gerding DN (August 1986). "Detection of Clostridium difficile toxins A (enterotoxin) and B (cytotoxin) in clinical specimens. Evaluation of a latex agglutination test". Am. J. Clin. Pathol. 86 (2): 208–11. PMID 3739972. 
  3. ^ Tucker KD, Carrig PE, Wilkins TD (May 1990). "Toxin A of Clostridium difficile is a potent cytotoxin". J. Clin. Microbiol. 28 (5): 869–71. PMC 267826. PMID 2112562. http://jcm.asm.org/cgi/pmidlookup?view=long&pmid=2112562. 
v · d · eToxins (enterotoxin/neurotoxin/hemotoxin/cardiotoxin/phototoxin)
Bacterial toxins
Gram positive
Cocci
Gram negative
Shiga toxin · Verotoxin/shiga-like toxin (E. coli) · E. coli heat-stable enterotoxin/enterotoxin · Cholera toxin · Pertussis toxin · Pseudomonas exotoxin · Extracellular adenylate cyclase
Lipopolysaccharide (Lipid A) · Bacillus thuringiensis delta endotoxin
Mycotoxins
Invertebrates
Vertebrates
note: some toxins are produced by lower species and pass through intermediate species

M: TOX

gen / txn

pto

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