- DPEP2
-
dipeptidase 2 Identifiers Symbol DPEP2 Entrez 64174 HUGO 23028 OMIM 609925 RefSeq NM_022355 UniProt Q9H4A9 Other data EC number 3.4.13.19 Locus Chr. 16 q22.1 Dipeptidase 2 (DPEP2) is a protein which in humans is encoded by the DPEP2 gene.[1]
DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation.[2]
References
- ^ Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (July 2003). "Identification of two additional members of the membrane-bound dipeptidase family". The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17 (10): 1313–5. doi:10.1096/fj.02-0899fje. PMID 12738806.
- ^ "Entrez Gene: Dipeptidase 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64174.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Hydrolase: proteases (EC 3.4) 3.4.11-19: Exopeptidase Dipeptidyl peptidase (Cathepsin C, Dipeptidyl peptidase-4) · Tripeptidyl peptidase (Tripeptidyl peptidase I, Tripeptidyl peptidase II)Other/ungrouped3.4.21-24: Endopeptidase Serine proteases · Cysteine protease · Aspartic acid protease · Metalloendopeptidases
Other/ungrouped: Amyloid precursor protein secretase (Alpha secretase, Beta-secretase 1, Beta-secretase 2, Gamma secretase)3.4.99: Unknown B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6 Precursor Prostanoids Leukotrienes 5-Lipoxygenase activating protein/Arachidonate 5-lipoxygenase
LTC4 synthase · Gamma-glutamyl transpeptidase · DPEP2Ungrouped Categories:- Genes on chromosome 16
- Chromosome 16 gene stubs
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