- PAQUID cohort
-
The PAQUID (or Paquid) cohort is a group of 3,777 individuals aged 65 years or older who were studied from 1988 until present. Researchers chose the group from at least 91 different areas of southwestern France to study the effects of different environmental, behavioral, and social vectors of age-related medical conditions and diseases. One of the major research goals was to determine some of the causes of dementia and Alzheimer's disease like, for example, the correlation between the levels of aluminum in drinking water and the occurrence of dementia.[1][2][3]
The studies were conducted by the Université Victor-Segalen, Bordeaux 2 (UB2) in Bordeaux, France.
The source of the term is "Personnes Agées QUID," which can be loosely translated from French and Latin as "What about the elderly?"[4]
See also
References
- ^ . PMID 9446147.
- ^ http://www.neurology.org/cgi/content/abstract/53/9/1953
- ^ Am J Epidemiol. 2009 Feb 15;169(4):489-96. Epub 2008 Dec 8. "Aluminum and silica in drinking water and the risk of Alzheimer's disease or cognitive decline: findings from 15-year follow-up of the PAQUID cohort." Rondeau V, Jacqmin-Gadda H, Commenges D, Helmer C, Dartigues JF.
- ^ http://www.pnas.org/content/98/14/8145.abstract
Biomedical research: Clinical study design / Design of experiments Overview Controlled study
(EBM I to II-1; A to B)Observational study
(EBM II-2 to II-3; B to C)Epidemiology/
methodsoccurrence: Incidence (Cumulative incidence) · Prevalence (Point prevalence, Period prevalence)
association: absolute (Absolute risk reduction, Attributable risk, Attributable risk percent) · relative (Relative risk, Odds ratio, Hazard ratio)
other: Virulence · Infectivity · Mortality rate · Morbidity · Case fatality · Specificity and sensitivity · Likelihood-ratios · Pre/post-test probabilityTrial/test types Analysis of clinical trials Risk–benefit analysis
Interpretation of results Categories:
Wikimedia Foundation. 2010.
