Butyrophenone

Butyrophenone

Chembox new
ImageFileL1=Butyrophenone.svg
ImageSizeL1=140px
ImageFileR1=Butyrophenone3d.pngImageSizeR1=140px
IUPACName=1-phenylbutan-1-one
OtherNames=|Section1= Chembox Identifiers
CASNo=
PubChem=10315
SMILES=CCCC(=O)C1=CC=CC=C1

Section2= Chembox Properties
Formula=C10H12O
MolarMass=148.202
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BoilingPt=
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Section3= Chembox Hazards
MainHazards=
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Butyrophenone is a chemical compound (a ketone); some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.

Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.

Examples include:

* Haloperidol, the most widely-used classical antipsychotic drug in this class
* Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment
* Benperidol, the most potent commonly-used antipsychotic (~ 200 times more potent as chlorpromazine)
* Triperidol, a highly-potent antipsychotic (100 times more potent than chlorpromazine)
* Melperone, a weakly-potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, in particular, in geriatric patients
* Lenperone
* Domperidone, a dopamine-antagonist antiemetic, derived further from butyrophenone (not being a butyrophenone itself).

The atypical antipsychotic risperidone, although not a butyrophenone, was developed with the structures of benperidol and lenperone as a basis.


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Look at other dictionaries:

  • Butyrophénone — Général …   Wikipédia en Français

  • butyrophénone — ● butyrophénone nom féminin Famille chimique de neuroleptiques, ayant une action antipsychotique surtout antihallucinatoire …   Encyclopédie Universelle

  • Butyrophenone — Als Butyrophenone wird eine Gruppe von Arzneistoffen bezeichnet, die sich vom Butyrophenon (1 Phenylbutan 1 on) ableiten und therapeutisch in der Psychiatrie zur Behandlung von Schizophrenien (d. h. als Antipsychotikum) eingesetzt werden.… …   Deutsch Wikipedia

  • butyrophenone — butirofenonas statusas T sritis chemija formulė C₆H₅COC₃H₇ atitikmenys: angl. butyrophenone rus. бутирофенон ryšiai: sinonimas – fenilpropilketonas …   Chemijos terminų aiškinamasis žodynas

  • butyrophenone — noun Etymology: butyr + phen + one Date: 1970 any of a class of antipsychotic drugs (as haloperidol) used especially in the treatment of schizophrenia …   New Collegiate Dictionary

  • butyrophenone — /byooh tir oh feuh nohn /, n. Pharm. any of a class of antipsychotics, as haloperidol, used to relieve symptoms of schizophrenia, acute psychosis, or other severe psychiatric disorders. [1940 45; BUTYR(IC) + O + PHEN + ONE] * * * …   Universalium

  • butyrophenone — noun Any of several pharmaceuticals used to treat psychiatric disorders …   Wiktionary

  • butyrophenone — One of a group of derivatives of 4 phenylbutylamine that have neuroleptic activity; e.g., haloperidol. * * * bu·ty·ro·phe·none .byüt ə (.)rō fə nōn n any of a class of antipsychotic drugs (as haloperidol) used esp. in the treatment of… …   Medical dictionary

  • butyrophenone — bu·ty·ro·phe·none …   English syllables

  • butyrophenone — n. one of a group of chemically related antipsychotic drugs that includes haloperidol and benperidol. Butyrophenones inhibit the effects of dopamine by occupying dopamine receptor sites in the body …   The new mediacal dictionary

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