Blue Brain

Blue Brain is a project, begun in May 2005, to create a computer simulation of the brain of mammals including the human brain, down to the molecular level. "Mission to build a simulated brain begins" (news), project of Institute at the École Polytechnique Fédérale de Lausanne (EPFL), Switzerland, "NewScientist", June 2005, webpage: [http://www.newscientist.com/article/dn7470.html NewSci7470] .] The aim is to study the brain's architectural and functional principles. The project was founded by Henry Markram from the Brain and Mind Institute at the École Polytechnique (EPFL) in Lausanne, Switzerland. and is based on 15 years of experimental data obtained from reverse engineering the microcircuitry of the neocortical column.

The project uses a Blue Gene supercomputer, running a simulation software, the MPI-based Neocortical Simulator (NCS) developed by Phil Goodman, to be combined with Michael Hines's NEURON software. The simulation will not consist of a mere artificial neural network, but will involve much more biologically realistic models of neurons.

The initial goal of the project, completed in December 2006 [cite web|url=http://bluebrain.epfl.ch/Jahia/site/bluebrain/op/edit/pid/19085|title=Project Milestones|work=Blue Brain|accessdate=2008-08-11] , was the simulation of a rat neocortical column, which can be considered the smallest functional unit of the neocortex (the part of the brain thought to be responsible for higher functions such as conscious thought). Such a column is about 2 mm tall, has a diameter of 0.5 mm and contains about 60,000 neurons in humans; rat neocortical columns are very similar in structure but contain only 10,000 neurons (and 10⁸ synapses). Between 1995 and 2005, Markram mapped the types of neurons and their connections in such a column.

In November 2007 [cite web|url=http://bluebrain.epfl.ch/page18700.html|title=News and Media information|work=Blue Brain|accessdate=2008-08-11] , the project reported the end of the first phase, delivering a data-driven process for creating, validating, and researching the neocortical column.

Now that the column is finished, the project is pursuing two separate goals:
# construction of a simulation on the "molecular level", which is desirable since it allows to study effects of gene expression;
# simplification of the column simulation to allow for parallel simulation of large numbers of connected columns, with the ultimate goal of simulating a whole neocortex (which in humans consists of about 1 million cortical columns.

See also

* Artificial intelligence
* Artificial neural network
* Artificial Society
* Important publications in computational sociology
* Artificial general intelligence
* Memristor
* Neural network
* Simulated reality
* Social simulation
* Virtual reality

Notes

References

* [http://www.forbes.com/technology/sciences/2005/06/06/cx_mh_0606ibm.html IBM Aims To Simulate A Brain] , Forbes, 6 June 2005.
* [http://www.newscientist.com/article.ns?id=dn7470 Mission to build a simulated brain begins] , New Scientist News, 6 June 2005.
* [http://bluebrain.epfl.ch/ Blue Brain Project site] , Lausanne.
* [http://bluebrain.epfl.ch/page18924.html FAQ on Blue Brain] .
* [http://brain.cse.unr.edu/ncsDocs/ NCS documentation] .
* [http://www.neuron.yale.edu/neuron/ NEURON documentation] .
* Henry Markram, "The Blue Brain Project", "Nature Neuroscience Review", 7:153-160, 2006 February. PMID 16429124.
* [http://www.spiegel.de/international/spiegel/0,1518,466789,00.html Growing a Brain in Switzerland] , Spiegel, 7 February 2007
* [http://www.seedmagazine.com/news/2008/03/out_of_the_blue.php Out of the Blue -- Can a thinking, remembering, decision-making, biologically accurate brain be built from a supercomputer?] , Seed Magazine, March 2008