Philip Seeman

Philip Seeman, OC, FRSC (born February 8, 1934) is a Canadian schizophrenia researcher and neuropharmacologist, known for his research on dopamine receptors.

Born in Winnipeg, Manitoba, Seeman was raised in Montreal. He received a Bachelor of Science degree, honours Physics & Physiology (1955), a Master of Science degree, Physiology of Transport & Secretion (1956), and a Doctor of Medicine (1960) from McGill University. In 1966, he received a Ph.D. in Life Sciences from Rockefeller University.

In 1967, Seeman became an Assistant Professor in the Department of Pharmacology at the University of Toronto. In 1970, he was appointed a Professor.

In 1974, having spent years in search for the binding site of antipsychotic medication, he discovered the dopamine D2 receptor, the basis for the dopamine hypothesis of schizophrenia.^[1][2]

In 2001, he was made an Officer of the Order of Canada "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".^[3] In 1985, he was made a Fellow of the Royal Society of Canada.^[4]

See also

• Baron Byng High School

References

1. ^ P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong (November 1975). "Brain receptors for antipsychotic drugs and dopamine: direct binding assays". Proceedings of the National Academy of Sciences of the United States of America 72 (11): 4376–4370. doi:10.1073/pnas.72.11.4376. PMC 388724. PMID 1060115. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=388724. 
2. ^ . PMC 1337253. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1337253. 
3. ^ Order of Canada
4. ^ http://www.sciandmed.com/sm/journalviewer.aspx?issue=1066&article=787&action=1

External links

• Home Page of Philip Seeman's Laboratory
• Probing the Biology of Psychosis, Schizophrenia, and Antipsychotics: An Expert Interview With Dr. Philip Seeman, MD, PhD - an interview on the Medscape website
• Schizophrenia - an essay by Philip Seeman, November 2001

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Name	Seeman, Philip
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Date of birth	February 8, 1934
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