Rifapentine

Rifapentine

drugbox
IUPAC_name = 3{ [(4-cyclopentyl-1-piperazinyl)imino] methyl}rifamycin


width = 250
CAS_number = 61379-65-5
ATC_prefix = J04
ATC_suffix = AB05
ATC_supplemental =
PubChem = 5462354
DrugBank = APRD01217
C=47 | H=64 | N=4 | O=12
molecular_weight = 877.031 g/mol
bioavailability = increases when administered with food
protein_bound =
metabolism =
elimination_half-life =
pregnancy_category =
legal_status =
routes_of_administration =

Rifapentine (INN, marketed under the brand name Priftin by Sanofi-Aventis) is an antibiotic drug used in the treatment of tuberculosis.

History

Rifapentine was first synthesized in 1965 by the same company that produced rifampin. The drug was approved by the Food and Drug Administration (FDA) in June 1998.

External links

*cite journal |author=Rosenthal IM, Zhang M, Williams KN, "et al" |title=Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model |journal=PLoS Medicine |volume=4 |issue=12 |pages=e344 |year=2007 |month=December |pmid=18092886 |pmc=2140085 |doi=10.1371/journal.pmed.0040344


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • rifapentine — noun An antibiotic drug used in the treatment of tuberculosis …   Wiktionary

  • rifapentine — rif·a·pen·tine (rif″ə penґtēn) a synthetic rifamycin antibiotic used in conjunction with other antituberculosis medications in the treatment of pulmonary tuberculosis; administered orally …   Medical dictionary

  • Rifamycin — The rifamycins are a group of antibiotics which are synthesized either naturally by the bacterium Amycolatopsis mediterranei , or artificially. They are a subclass of the larger family, Ansamycin. Rifamycins are particularly effective against… …   Wikipedia

  • Tuberculosis treatment — Various pharmaceutical tuberculosis treatments their actions Tuberculosis treatment refers to the medical treatment of the infectious disease tuberculosis (TB). The standard short course treatment for TB is isoniazid, rifampicin (also known as… …   Wikipedia

  • Dapsone — Systematic (IUPAC) name 4 [(4 aminobenzene)sulfonyl]aniline …   Wikipedia

  • Rifabutin — Systematic (IUPAC) name (9S,12E,14S,15R,16S,17R,18R,19R,20S, 21S,22E,24Z) 6,16,18,20 tetrahydroxy 1 isobutyl 14 methoxy 7,9,15,17,19,21,25 hepta methyl spiro[9,4 (epoxypentadeca [1,11 …   Wikipedia

  • tuberculosis — /too berr kyeuh loh sis, tyoo /, n. Pathol. 1. an infectious disease that may affect almost any tissue of the body, esp. the lungs, caused by the organism Mycobacterium tuberculosis, and characterized by tubercles. 2. this disease when affecting… …   Universalium

  • Dihydropteroate synthase inhibitor — A dihydropteroate synthetase inhibitor is a drug that inhibits the action of dihydropteroate synthetase. Most are sulfonamides. Tetrahydrofolate synthesis pathway In bacteria, antibacterial sulfonamides act as competitive inhibitors of the enzyme …   Wikipedia

  • Ciprofloxacin — Not to be confused with Cipralex, a brand name of the antidepressant escitalopram. Cipro redirects here. For the Rome Metro station, see Cipro (Rome Metro). Ciprofloxacin …   Wikipedia

  • Leprosy — For the Hebrew Bible term and its varied meanings, see Tzaraath. For other uses, see Leprosy (disambiguation). Leprosy Classification and external resources A 24 year old man infected with leprosy. ICD 10 …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”