Conduritol

Conduritol

Conduritol or 1,2,3,4-cyclohexenetetrol is any of six isomeric organic compounds with chemical formula C6H10O4, that can be seen as derivatives of cyclohexene with four hydroxyl groups (OH) replacing hydrogen atoms on the four carbon atoms not adjacent to the double bond. They are therefore cyclic polyols or cyclitols.[1]

The six isomers (called A, B, C, D, E, F) differ by the positions of the hydroxyls relative to the mean plane of the ring. Conduritol.svg

Only the A and B isomers have been found in nature. The first conduritol was isolated in 1908 by K. Kübler[2] from the bark of the vine Marsdenia condurango, hence its name. A number of conduritol derivatives has antifeedant, antibiotic, antileukemic, and growth-regulating activity. Also some conduritol derivatives show interesting biological properties including tumour-inhibitory, antileukaemic, and antibiotic activities.

The PubChem catalog id of Conduritol B is 65317, and its CAS number is 25348-64-5. The molar mass is 146.1412 g/mol and the exact mass is 146.057909.

See also

References

  1. ^ (1990) Tetrahedron, Vol 46, No 11, 3715 - 3742.
  2. ^ K. Kübler (1908), Arch. Phann. Ber. Stsch. Pharm. 246,620.