Isomerase

Isomerase

In biochemistry, an isomerase is an enzyme that catalyses the structural rearrangement of isomers. Isomerases thus catalyze reactions of the form

:A → B

Nomenclature

The names of isomerases are formed as "substrate" isomerase" (for example, enoyl CoA isomerase), or as "substrate" "type of isomerase" (for example, phosphoglucomutase).

Classification

Isomerases have their own EC classification of enzymes: EC 5. Isomerases can be further classified into six subclasses:
* includes enzymes that catalyze racemization (racemases) and epimerization (epimerases)
* includes enzymes that catalyze the isomerization of geometric isomers (cis-trans isomerases)
* includes intramolecular oxidoreductases
* includes intramolecular transferases (mutases)
* includes intramolecular lyases
* includes other isomerases (including topoisomerases)

References

* [http://www.chem.qmul.ac.uk/iubmb/enzyme/EC5/intro.html EC 5 Introduction] from the Department of Chemistry at Queen Mary, University of London

External links

* [http://www.gopubmed.org/GoMeshPubMed/gomeshpubmed/?tool=HotTopicDirect&termAlt=mesh%237535 GoPubMed: Top authors, journals, places publishing on Isomerases]


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Look at other dictionaries:

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  • isomérase — ● isomérase nom féminin Enzyme qui catalyse des réarrangements intramoléculaires (par exemple la transformation d une forme L en forme D ou d une forme cis en forme trans) …   Encyclopédie Universelle

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  • isomerase — /uy som euh rays , rayz /, n. Biochem. any of a class of enzymes that catalyze reactions involving intramolecular rearrangements. [1940 45; ISOMER + ASE] * * * ▪ enzyme       any one of a class of enzymes that catalyze reactions involving a… …   Universalium

  • Isomerase — I|so|me|ra|se [↑ Isomer (1) u. ↑ ase], die; , n: Bez. für die 5. Klasse der Enzyme. Hauptvertreter der ↑ Isomerisierungen katalysierenden Enzyme sind Epimerasen, Racemasen, intramol. Oxidoreduktasen (z. B. ↑ Glucose Isomerase), Tautomerasen,… …   Universal-Lexikon

  • isomerase — izomerazė statusas T sritis chemija apibrėžtis Fermentas, katalizuojantis izomerizacijos reakciją. atitikmenys: angl. isomerase rus. изомераза …   Chemijos terminų aiškinamasis žodynas

  • isomerase — noun Date: 1927 an enzyme that catalyzes the conversion of its substrate to an isomeric form …   New Collegiate Dictionary

  • isomerase — noun Any enzyme which catalyzes the conversion of one isomeric form of a chemical compound to another …   Wiktionary

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