- MASP1 (protein)
protein
Name = mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
caption =
width =
HGNCid = 6901
Symbol = MASP1
AltSymbols = CRARF, PRSS5
EntrezGene = 5648
OMIM = 600521
RefSeq = NM_001879
UniProt = P48740
PDB =
ECnumber =
Chromosome = 3
Arm = q
Band = 27
LocusSupplementaryData = -q28Mannose-associated serine protease 1 (MASP1) is a human
gene .cite journal | author = Takada F, Takayama Y, Hatsuse H, Kawakami M | title = A new member of the C1s family of complement proteins found in a bactericidal factor, Ra-reactive factor, in human serum | journal = Biochem. Biophys. Res. Commun. | volume = 196 | issue = 2 | pages = 1003–9 | year = 1993 | month = October | pmid = 8240317 | doi = 10.1006/bbrc.1993.2349 | url = | issn = ] cite journal | author = Sato T, Endo Y, Matsushita M, Fujita T | title = Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein | journal = Int. Immunol. | volume = 6 | issue = 4 | pages = 665–9 | year = 1994 | month = April | pmid = 8018603 | url = | issn = ]The
protein encoded by this gene is involved in the lectin pathway of thecomplement system and is responsible for cleaving C4 and C2 to form C4b2a, aC3-convertase .cite journal | author = Matsushita M, Thiel S, Jensenius JC, Terai I, Fujita T | title = Proteolytic activities of two types of mannose-binding lectin-associated serine protease | journal = J. Immunol. | volume = 165 | issue = 5 | pages = 2637–42 | year = 2000 | month = September | pmid = 10946292 | url = http://www.jimmunol.org/cgi/content/abstract/165/5/2637 | issn = ]ee also
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mannan-binding lectin References
External links
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