Dihydropyrimidine dehydrogenase
- Dihydropyrimidine dehydrogenase
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Dihydropyrimidine dehydrogenase (DPD) is an enzyme that is involved in pyrimidine degradation. It is the initial and rate-limiting step in pyrimidine catabolism. It catalyzes the reduction of uracil and thymine. It is also involved in the degradation of the chemotherapeutic drugs 5-fluorouracil and Tegafur-uracil.
See also
External links
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| Pyrimidine metabolism |
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| Deoxyribonucleotides |
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mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m
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k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon
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m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
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Categories:
- Genes on chromosome 1
- Enzyme stubs
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Dihydropyrimidine dehydrogenase deficiency — Classification and external resources OMIM 274270 DiseasesDB 29817 MeSH … Wikipedia
Dihydropyrimidine dehydrogenase (NADP+) — Identifiers EC number 1.3.1.2 CAS number 9029 01 0 … Wikipedia
dihydropyrimidine dehydrogenase — An enzyme in pyrimidine biosynthesis that reacts 5,6 dihydrouracil with NADP+ to form uracil and NADPH; it also acts on dihydrothymine; a deficiency of this enzyme can result in hyperuracil thyminuria. SYN: dihydrouracil dehydrogenase … Medical dictionary
dihydropyrimidine dehydrogenase (NADP+) — di·hy·dro·py·rim·i·dine de·hy·dro·gen·ase (NADP+) (di hi″dro pə rimґĭ dēn de hiґdro jən ās) [EC 1.3.1.2] an enzyme of the oxidoreductase class that catalyzes the dehydrogenation of uracil and of thymine, using NADPH … Medical dictionary
Dihydroorotate dehydrogenase — Dihydroorotate oxidase Identifiers EC number 1.3.3.1 CAS number 9029 03 2 … Wikipedia
Dihydrouracil dehydrogenase (NAD+) — Identifiers EC number 1.3.1.1 CAS number 9026 89 5 … Wikipedia
dihydrouracil dehydrogenase — SYN: dihydropyrimidine dehydrogenase … Medical dictionary
dihydrouracil dehydrogenase (NADP+) — di·hy·dro·ura·cil de·hy·dro·gen·ase (NADP+) (di hi″dro ūrґə sĭl de hiґdro jən ās) dihydropyrimidine dehydrogenase (NADP) … Medical dictionary
DHPDH — dihydropyrimidine dehydrogenase … Medical dictionary
DHPDH — • dihydropyrimidine dehydrogenase … Dictionary of medical acronyms & abbreviations
