ISU

ISU may refer to:

* ISU-152, ISU-122, Soviet self-propelled guns
* International Skating Union
* International Seamen's Union
* Independent Study Unit
* Immigration Service Union
* Industry Specific Solution for Utilities, a SAP module
* Isu Station on the Seoul Metropolitan Subway
* Isu, a local government area of Imo State, Nigeria
* Isu, a town in Cameroon

Universities:
* Idaho State University, Pocatello, Idaho
* Illinois State University, Normal, Illinois
* Indiana State University, Terre Haute, Indiana
* International Space University, Illkirch-Graffenstaden, France
* Iowa State University, Ames, Iowa