Acetohydroxamic acid

Acetohydroxamic acid

drugbox
IUPAC_name = ethanehydroxamic acid



CAS_number = 546-88-3
ChemSpiderID = 1913
ATC_prefix = G04
ATC_suffix = BX03
ATC_supplemental =
PubChem = 1990
DrugBank = APRD00774
C=2 | H=5 | N=1 | O=2
molecular_weight = 75.0666 g/mol
bioavailability =
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elimination_half-life =
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Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme (Fishbein and Carbone, 1965).

References

* W. Fishbein and P. Carbone "J Biol Chem." 1965 Jun;240:2407-14


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