Iodine-123 (123I) is a radioactive
isotopeof iodineused in nuclear medicineimaging, including single photon emission computed tomography(SPECT).
Iodine-123 is produced in a
cyclotronby protonirradiation of enriched xenon. Its half-lifeis 13.22 hours; the decay emits gamma radiationwith predominant energies of 159 keVand 27 keV. In medical applications this radiation can be detected by a gamma camera.
Iodine-123 is supplied as a solution of
sodium iodide. This is administered to a patient by intravenous injection or as a drink1. The iodine is taken up by the thyroid glandand a gamma camerais used to form functional images of the thyroidfor diagnosis. Quantitative measurements of the thyroid can be performed to calculate the iodine uptake for the diagnosis of hypothyroidism.
Iodine-123 is also used as a label in other
Isotopes of iodine
1. Sharp PF, Gemmell HG, Smith FW (eds). Practical nuclear medicine 2nd edition. 1998 Oxford University Press.
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