Loteprednol

Loteprednol

drugbox
IUPAC_name = chloromethyl 17-ethoxycarbonyloxy- 11-hydroxy- 10,13-dimethyl-3-oxo- 7,8,9,11,12,14,15, 16-octahydro- 6"H"-cyclopenta [a] phenanthrene-17-carboxylate



imagename = Loteprednol etabonate
CAS_number = 82034-46-6
ATC_prefix = S01
ATC_suffix = BA14
ATC_supplemental =
PubChem = 444025
DrugBank = APRD01078
C=24 | H=31 | Cl=1 | O=7
molecular_weight = 466.951 g/mol
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US = C
pregnancy_category =
legal_AU =
legal_UK =
legal_US = Rx-only
legal_status =
routes_of_administration =

Loteprednol (as the ester loteprednol etabonate) is a corticosteroid used in ophthalmology.

In the US, it is marketed by Bausch and Lomb as Lotemax.

Ocular applications for this drug include the treatment of chronic forms of keratitis (e.g.: adenoviral and Thygeson’s keratitis), vernal keratoconjunctivitis, pingueculitis, and episcleritis. Its use has little or no effect on IOP


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