- CD155
Protein
Name=CD155
Symbol=CD155
caption= Poliovirus (in red and blue) bound to CD155 (purple)
AltSymbols=HVED, Necl-5, NECL5, Tage4
HGNCid=
Chromosome=19
Arm=q
Band=13.2
LocusSupplementaryData=
ECnumber=
OMIM=173850
EntrezGene=5817
RefSeq=NM_006505
UniProt=P15151CD155 is a Type I
transmembrane glycoprotein in theimmunoglobulin superfamily. [cite journal |author=Mendelsohn CL, Wimmer E, Racaniello VR |title=Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily |journal=Cell |volume=56 |issue=5 |pages=855–65 |year=1989 |pmid=2538245 |doi=] Commonly known as "Poliovirus Receptor" (PVR) due to its involvement in the cellularpoliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellularadherens junction s betweenepithelial cell s.cite journal |author=Maier MK, Seth S, Czeloth N, "et al" |title=The adhesion receptor CD155 determines the magnitude of humoral immune responses against orally ingested antigens |journal= |volume= |issue= |pages= |year=2007 |pmid=17621371 |doi=10.1002/eji.200737072] The role of CD155 in theimmune system is unclear, though it may be involved in intestinal humoral immune responses.References
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