Cr mimetic

Cr mimetic

Caloric restriction mimetics try to mimic the substantial anti-aging effects caloric restriction has on many laboratory animals.

Candidate compounds include:
*Resveratrol is found in red wine and grapesFact|date=December 2007. Many supplement companies market inexpensive concentrates.
*metformin mimics the gene expression of CR miceFact|date=December 2007, and has extended mice's maximum life spansFact|date=December 2007. It is already clinically approved to treat diabetes.
*Lipoic Acid (α-Lipoic Acid, Alpha Lipoic Acid, or ALA)Fact|date=December 2007
*2-deoxy-D-glucose, or 2-DGcite journal |author=Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M |title=Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress |journal=Cell Metab. |volume=6 |issue=4 |pages=280–93 |year=2007 |pmid=17908557 |doi=10.1016/j.cmet.2007.08.011] . 2-DG interferes in glycolysis, starving a cell of fuel.
*IodoacetateFact|date=December 2007

References

External links

* [http://www.cron-web.org/cr-mimetics.html A List of Potential CR Mimetics]
* [http://www.r-lipoic.com R-Lipoic Acid: A Possible Anti-Aging Intervention]


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  • mimetic — MIMÉTIC, Ă, mimetici, ce, adj. Care se referă la mimetism, care are mimetism. – Din fr. mimétique. Trimis de LauraGellner, 31.05.2004. Sursa: DEX 98  mimétic adj. m., pl. mimétici; f. sg., mimétică, pl …   Dicționar Român

  • Mimetic drift — describes the flow of ideas (memes) across a social group. A typical usage can be seen in the edition of The Harrow Technology Report dated 22 December 2003.[1] The phrase was used as the title of a short story by science fiction author Glenn… …   Wikipedia

  • Mimetic — has several different uses: * In mathematics, see mimetic (mathematics) * In biology and ecology, see mimicry * In acting and literary theory, see mimesis * In linguistics, see Japanese sound symbolism * For the study of memes, see memetics …   Wikipedia

  • Mimetic isomorphism — in organization theory refers to the tendency of an organization to imitate another organization s structure because of the belief that the structure of the latter organization is beneficial. An example for this is a family company transforming… …   Wikipedia

  • mimetic — (adj.) 1630s, having an aptitude for mimicry, from Gk. mimetikos imitative, good at imitating, from mimetos, verbal adjective of mimeisthai to imitate. Originally of persons, attested of animals or plants from 1851. Related: Mimetical (1610s);… …   Etymology dictionary

  • mimetic — ► ADJECTIVE ▪ relating to or practising mimesis or mimicry …   English terms dictionary

  • mimetic — [mi met′ik, mīmēt′ik] adj. [Gr mimētikos < mimeisthai, to imitate < mimos, actor] 1. of or characterized by imitation; imitative 2. of or characterized by mimicry mimetically adv …   English World dictionary

  • Mimetic (mathematics) — The goal of numerical analysis is to approximate the continuum, so instead of solving a partial differential equation one aims in solve a discrete version of the continuum problem. A numerical method is called mimetic when it mimics (or imitates) …   Wikipedia

  • mimetic — [[t]mɪme̱tɪk[/t]] ADJ: usu ADJ n Mimetic movements or activities are ones in which you imitate something. [FORMAL] Both realism and naturalism are mimetic systems or practices of representation …   English dictionary

  • mimetic — adjective Etymology: Late Latin mimeticus, from Greek mimētikos, from mimeisthai to imitate, from mimos mime Date: 1637 1. imitative 2. relating to, characterized by, or exhibiting mimicry < mimetic coloring of a butterfly > • mimetically adverb …   New Collegiate Dictionary

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