John Robert Vane


John Robert Vane

Infobox Scientist
name = John Robert Vane
box_width =


image_width =150px
caption =John Robert Vane
birth_date = March 29, 1927
birth_place =
death_date = November 19, 2004
death_place =
residence =
citizenship =
nationality = British
ethnicity =
field = pharmacology
work_institutions =
alma_mater =
doctoral_advisor =
doctoral_students =
known_for = aspirin, prostaglandin
author_abbrev_bot =
author_abbrev_zoo =
influences =
influenced =
prizes = Nobel Prize in Physiology or Medicine in 1982
religion =
footnotes =

Sir John Robert Vane (March 29, 1927 – November 19, 2004) was a British pharmacologist. His father was the son of immigrants from Russia and his mother came from a Worcestershire farming family. He was educated at King Edward's School in Edgbaston, Birmingham, and studied Chemistry at the University of Birmingham in 1944. Vane completed a doctorate in pharmacology from the University of Oxford in 1953.

He held a post at the Institute of Basic Medical Sciences of the University of London in the Royal College of Surgeons of England for 18 years. During that time he developed certain bioassay techniques that led to important scientific discoveries. He won a Nobel Prize in Physiology or Medicine in 1982 for his work on aspirin in which he discovered it inhibited prostaglandin biosynthesis [Citation
id = PMID:1149792
url= http://www.ncbi.nlm.nih.gov/pubmed/1149792
last=Moncada
first=S
last2=Ferreira
first2=S H
last3=Vane
first3=J R
publication-date=1975 Apr
year=1975
title=Inhibition of prostaglandin biosynthesis as the mechanism of analgesia of aspirin-like drugs in the dog knee joint.
volume=31
issue=2
periodical=Eur. J. Pharmacol.
pages=250-60
] [Citation
id = PMID:4199867
url= http://www.ncbi.nlm.nih.gov/pubmed/4199867
last=Ferreira
first=S H
last2=Moncada
first2=S
last3=Vane
first3=J R
publication-date=1973 Mar
year=1973
title=Further experiments to establish that the analgesic action of aspirin-like drugs depends on the inhibition of prostaglandin biosynthesis.
volume=47
issue=3
periodical=Br. J. Pharmacol.
pages=629P-630P
] [Citation
id = PMID:5284362
url= http://www.ncbi.nlm.nih.gov/pubmed/5284362
last=Ferreira
first=S H
last2=Moncada
first2=S
last3=Vane
first3=J R
publication-date=1971 Jun 23
year=1971
title=Indomethacin and aspirin abolish prostaglandin release from the spleen.
volume=231
issue=25
periodical=Nature New Biol.
pages=237-9
] [Citation
id = PMID:5284360
url= http://www.ncbi.nlm.nih.gov/pubmed/5284360
last=Vane
first=J R
publication-date=1971 Jun 23
year=1971
title=Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.
volume=231
issue=25
periodical=Nature New Biol.
pages=232-5
] .

In 1973, Vane left academia and took up the position of director of research of the Wellcome Foundation. Twelve years later, however, he returned to academic life at the William Harvey Research Institute at the Medical College of St Bartholomew's Hospital (now Barts and The London, Queen Mary's School of Medicine and Dentistry). [cite web | url = http://www.qmul.ac.uk/alumni/alumninetwork/notablealumni/index.html | title = Queen Mary, University of London Notable Alumni and Staff | accessdate = 2007-09-23]

References


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • John Robert Vane — (* 29. März 1927 in Tardebigg, Worcestershire; † 19. November 2004 in Farnborough (London)) war ein britischer Biochemiker und Medizin Nobelpreisträger. Er war der Entdecker der Funktionsweise von Aspirin. Leben Sein Vater Maurice Vane war Sohn… …   Deutsch Wikipedia

  • John Robert Vane — John Vane John Vane (né le 29 mars 1927, mort le 19 novembre 2004), était un médecin et pharmacologue britannique, lauréat du prix Nobel de médecine. Biographie Sir John Robert Vane est né le 29 mars 1927 à Tardebigg dans le… …   Wikipédia en Français

  • John Robert Vane — ( * 29 de marzo de 1927 19 de noviembre de 2004) nació en Birmingham, Inglaterra en 1927. Estudió farmacología en la Universidad de Birmingham y en la Universidad de Oxford. Obtiene el Premio Nobel de Fisiología o Medicina en 1982, compartido con …   Wikipedia Español

  • John Robert Vane — nació en Birminghan, Inglaterra en 1927. Estudió famacología en la Universidad de Birminghan y en la Universidad de Oxford. Obtiene el Premio Nobel de Fisiología o Medicina en 1982, compartido con Sune Bergstrom y Bengt Samuelsson, por sus… …   Enciclopedia Universal

  • Medizinnobelpreis 1982: Sune Bergström — Bengt Ingemar Samuelsson — John Robert Vane —   Die beiden Schweden und der Brite wurden für ihre Entdeckung der Prostaglandine und verwandte biologisch aktive Substanzen ausgezeichnet.    Biografien   Sune Karl Bergström, * Stockholm 10. 1. 1916; 1947 58 Professor in Lund und dann bis 1980… …   Universal-Lexikon

  • John R. Vane — John Robert Vane (* 29. März 1927 in Tardebigg, Worcestershire; † 19. November 2004 in Farnborough) war ein britischer Biochemiker und Medizin Nobelpreisträger. Er war der Entdecker der Funktionsweise von Aspirin. Leben Sein Vater Maurice Vane… …   Deutsch Wikipedia

  • Vane, Sir John Robert — ▪ 2005       British pharmacologist (b. March 29, 1927, Tardebigg, Worcestershire, Eng. d. Nov. 19, 2004, Farnborough, Kent, Eng.), conducted pioneering research in the study of hormonelike substances in the body called prostaglandins; he shared… …   Universalium

  • Vane , Sir John Robert — (1927–) British pharmacologist Vane studied chemistry at the University of Birmingham and pharmacology at Oxford, where he obtained his DPhil in 1953. He then worked at the Royal College of Surgeons, serving as professor of experimental… …   Scientists

  • John Vane — John Robert Vane (* 29. März 1927 in Tardebigg, Worcestershire; † 19. November 2004 in Farnborough) war ein britischer Biochemiker und Medizin Nobelpreisträger. Er war der Entdecker der Funktionsweise von Aspirin. Leben Sein Vater Maurice Vane… …   Deutsch Wikipedia

  • Vane — is a surname, and may refer to:* Ben Vane * Charles Vane * Charles Vane Tempest Stewart, 6th Marquess of Londonderry * Charles Vane Tempest Stewart, 7th Marquess of Londonderry * Christopher Vane, 1st Baron Barnard * Edith Vane Tempest Stewart,… …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.