Cushing ulcer

Cushing ulcer
Cushing ulcer
Classification and external resources
DiseasesDB 3259

A Cushing ulcer is a gastric ulcer produced by elevated intracranial pressure. It is also called von Rokitansky-Cushing syndrome. Apart from in the stomach, it may also develop in the proximal part of the duodenum and the distal esophagus.

It is named for Harvey Cushing.[1][2]

Causes

One possible explanation for the development of Cushing ulcers is the stimulation of vagal nuclei due to the increased intracranial pressure which leads to increased secretion of gastric acid. The vagus nerve releases acetylcholine, which stimulates the M3 receptor on the parietal cell and activates the second messenger to stimulate IP3/Ca2+ to stimulate the Hydrogen/Potassium ATPase pump which will increase gastric acid production.

May also be a direct result of Cushing reaction.

See also

  • Curling ulcer

References

  1. ^ synd/982 at Who Named It?
  2. ^ H. Cushing. Peptic ulcer and the interbrain. Surg Obst, 1932, 55: 1-34.




Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Cushing ulcer — Cushing Rokitansky ulcer a small peptic ulcer, usually occurring in groups, associated with manifest or occult lesions of the central nervous system. Called also Rokitansky Cushing u …   Medical dictionary

  • Rokitansky-Cushing ulcer — Cushing u …   Medical dictionary

  • Cushing — may refer to: Places in the United States Cushing, Iowa Cushing, Maine Cushing, Minnesota Cushing Township, Minnesota Cushing, Nebraska Cushing, Oklahoma Cushing, Texas Cushing, Wisconsin Cushing Island, Maine People Alonzo Cushing (1841 1863), U …   Wikipedia

  • Cushing — Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom. Cushing peut faire référence à : Cushing, une localité du comté de Woodbury dans l Iowa, Cushing, une localité du Comté de Knox dans le Maine,… …   Wikipédia en Français

  • Ulcer — duodenal ulcer. Ulcers are healing wounds that develop on the skin, mucous membranes, or eye. Although they have many causes, they are marked by: # Loss of integrity of the area # Secondary infection of the site by bacteria, fungus or virus #… …   Wikipedia

  • Cushing disease response (phenomenon reflex) etc. — Cush·ing disease, response (phenomenon, reflex), etc. (kooshґing) [Harvey Williams Cushing, American surgeon, 1869–1939] see under disease, response, syndrome, and ulcer. See also equine Cushing disease, under disease …   Medical dictionary

  • Curling's ulcer — Classification and external resources DiseasesDB 3237 MeSH D004381 Curling s ulcer is an acute …   Wikipedia

  • Peptic ulcer — Classification and external resources Deep gastric ulcer ICD 10 K25–K …   Wikipedia

  • Rokitansky-Cushing ulcers — Ro·ki·tan·sky Cush·ing ulcers (ro″kĭ tahnґske kooshґing) [K.F. von Rokitansky; Harvey Williams Cushing, American surgeon, 1869–1939] see under ulcer …   Medical dictionary

  • Management of ulcerative colitis — involves first treating the acute symptoms of the disease, then maintaining remission. Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes characteristic ulcers, or open… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”