Hydrastinine

Hydrastinine

Drugbox
IUPAC_name = "1,3-dioxolo(4,5-g)isoquinolin-5-ol, 5,6,7,8-tetrahyro-6-methyl- 5,6,7,8-Tetrahydro-6-methyl- 1,3-dioxolo(4,5-g) isoquinolin-5-ol"



width = 150
CAS_number = 6592-85-4
ATC_prefix =
ATC_suffix =
ATC_supplemental =
PubChem = 3638
DrugBank =
C=11 | H=13 | N=1 | O=3
molecular_weight = 207.226
bioavailability =
metabolism = Hepatic
elimination_half-life=
excretion = Renal
pregnancy_category = ?
legal_status =
routes_of_administration =

Hydrastinine is a semisynthetic alkaloid from the hydrolysis of the alkaloid hydrastine, which was found naturally in small quantites in "Hydrastis canadensis" L. (Ranunculaceae). Hydrastinine was produced by oxidative splitting of hydrastine hydrochloride with nitric acid in good yield. The drug was patented by Bayer as a haemostatic drug during 1910s.


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  • hydrastinine — /huy dras teuh neen , nin/, n. Pharm. a white, crystalline, poisonous alkaloid, C11H13NO3, synthesized from hydrastine: used to arrest bleeding, esp. in the uterus. [1885 90; HYDRASTINE + INE2] * * * …   Universalium

  • hydrastinine — A semisynthetic alkaloid prepared from hydrastine; the hydrochloride has been used in uterine hemorrhage and as an oxytocic; in large doses, it is a powerful depressant of the entire motor system (m …   Medical dictionary

  • hydrastinine — n. synthetic alkaloid used as a medication to control uterine bleeding …   English contemporary dictionary

  • hydrastinine — hy·dras·ti·nine …   English syllables

  • hydrastinine — /haɪˈdræstənin/ (say huy drastuhneen), / naɪn/ (say nuyn) noun a substance used as a heart stimulant or to control uterine haemorrhage. {German hydrastinin} …  

  • hydrastinine — hīˈdrastəˌnēn, nə̇n noun ( s) Etymology: International Scientific Vocabulary hydrastine + ine; probably originally formed as German hydrastinin : a crystalline base C11H13NO3 formed by the oxidation of hydrastine and useful in controlling uterine …   Useful english dictionary

  • Methylenedioxymethamphetamine — drugbox IUPAC name = (±) 1 (benzo [ d ] [1,3] dioxol 5 yl) N methylpropan 2 amine CAS number = 69610 10 2 ChemSpiderID = 1556 PubChem = 1615 C = 11 | H = 15 | N = 1 | O = 2 molecular weight = 193.25 g/mol smiles = CC(NC)CC1=CC=C(OCO2)C2=C1… …   Wikipedia

  • MDMA — Systematic (IUPAC) name (RS) 1 (benzo[d][1,3]dioxol 5 …   Wikipedia

  • Goldenseal — Conservation status Apparently Secure (NatureServe) …   Wikipedia

  • Hydrastine — Drugbox IUPAC name = 6,7 dimethoxy 3 (5,6,7,8 tetrahydro 6 methyl 1,3 dioxolo(4,5 g)isoquinoline 5 yl) 1(3H) isobenzo furan width = 150 CAS number = 118 08 1 ATC prefix = ATC suffix = ATC supplemental = PubChem = 1309 DrugBank = C=21 | H=21 | N=1 …   Wikipedia

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