Proparacaine

Proparacaine

Drugbox



IUPAC_name = 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate
CAS_number = 499-67-2
ATC_prefix=N01
ATC_suffix=BA04
ATC_supplemental=
PubChem=10367247
DrugBank=APRD00522
C = 16 | H = 26 | N = 2 | O = 3
molecular_weight = 294.389 g/mol
bioavailability = n/a
metabolism =plasma
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =C
legal_AU =
routes_of_administration = Topical

Proparacaine (Alcaine, Ak-Taine) is a topical anesthetic drug of the amino ester group. It is indicated for use as an ophthalmic anesthetic, to reduce pain and discomfort during procedures involving the eye. Proparacaine is available as its hydrochloride salt in ophthalmic solutions at a concentration of 0.5%. It is believed the drug exerts an effect on voltage gated sodium channels (as an antagonist) to affect the permeability of neuronal membranes; how this inhibits pain sensations and the exact mechanism of action of proparacaine are, however, unknown.


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • proparacaine — pro·par·a·caine prō par ə .kān n a drug used in the form of its hydrochloride C16H26N2O3·HCl as a topical anesthetic …   Medical dictionary

  • proparacaine hydrochloride — A surface anesthetic agent used in ophthalmology. SYN: proxymetacaine hydrochloride. * * * pro·par·a·caine hy·dro·chlo·ride (pro parґə kān) [USP] an anesthetic, applied topically to the conjunctiva …   Medical dictionary

  • Cocaine — For other uses, see Cocaine (disambiguation). Cocaine …   Wikipedia

  • Local anesthetic — A local anesthetic is a drug that causes reversible local anesthesia and a loss of nociception. When it is used on specific nerve pathways (nerve block), effects such as analgesia (loss of pain sensation) and paralysis (loss of muscle power) can… …   Wikipedia

  • Tonometry — In music, a tonometer is an instrument used to determine the pitch or vibration rate of tones, such as a tuning fork. Tonometry is the measurement of tension or pressure [http://www.mercksource.org/pp/us/cns/cns hl… …   Wikipedia

  • Oxybuprocaine — Systematic (IUPAC) name 2 diethylaminoethyl 4 amino 3 butoxy benzoate Clinical data AHFS/Drugs.com …   Wikipedia

  • Topical anesthetic — A topical anesthetic is a local anesthetic that is used to numb the surface of a body part. They can be used to numb the front of the eye, the inside of the nose, the throat, the skin, the ear, the anus, and the genital area… …   Wikipedia

  • List of cocaine analogues — Cocaine with it s numerical substitution positions. This is a list of cocaine analogues. A cocaine analogue retains 3β benzoyloxy or similar functionality unlike phenyltropanes. Cocaine analogues proper consist of the nine following classes of… …   Wikipedia

  • Crack cocaine — A pile of crack cocaine ‘rocks’ Crack cocaine is the freebase form of cocaine that can be smoked. It may also be termed rock, hard, iron …   Wikipedia

  • proxymetacaine hydrochloride — SYN: proparacaine hydrochloride …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”