[cite web | title = Entrez Gene: SFTPB surfactant, pulmonary-associated protein B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6439| accessdate = ] ]"Pulmonary surfactant-associated protein B"' is a membrane protein which manufactures surfactant.
Humans and animals born with a congenital absence of SP-B suffer from intractable respiratory failure.
ee also
* Pulmonary_surfactant#Proteins
References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Pérez-Gil J |title=Lipid-protein interactions of hydrophobic proteins SP-B and SP-C in lung surfactant assembly and dynamics. |journal=Pediatric pathology & molecular medicine |volume=20 |issue= 6 |pages= 445–69 |year= 2002 |pmid= 11699574 |doi=
*cite journal | author=Johansson J, Curstedt T, Robertson B |title=Artificial surfactants based on analogues of SP-B and SP-C. |journal=Pediatric pathology & molecular medicine |volume=20 |issue= 6 |pages= 501–18 |year= 2002 |pmid= 11699576 |doi=
*cite journal | author=Nogee LM |title=Alterations in SP-B and SP-C expression in neonatal lung disease. |journal=Annu. Rev. Physiol. |volume=66 |issue= |pages= 601–23 |year= 2004 |pmid= 14977415 |doi= 10.1146/annurev.physiol.66.032102.134711
*cite journal | author=Moore KJ, D'Amore-Bruno MA, Korfhagen TR, "et al." |title=Chromosomal localization of three pulmonary surfactant protein genes in the mouse. |journal=Genomics |volume=12 |issue= 2 |pages= 388–93 |year= 1992 |pmid= 1346779 |doi=
*cite journal | author=Voorhout WF, Veenendaal T, Haagsman HP, "et al." |title=Intracellular processing of pulmonary surfactant protein B in an endosomal/lysosomal compartment. |journal=Am. J. Physiol. |volume=263 |issue= 4 Pt 1 |pages= L479–86 |year= 1992 |pmid= 1415726 |doi=
*cite journal | author=Johansson J, Jörnvall H, Curstedt T |title=Human surfactant polypeptide SP-B. Disulfide bridges, C-terminal end, and peptide analysis of the airway form. |journal=FEBS Lett. |volume=301 |issue= 2 |pages= 165–7 |year= 1992 |pmid= 1568474 |doi=
*cite journal | author=Yu SH, Possmayer F |title=Effect of pulmonary surfactant protein B (SP-B) and calcium on phospholipid adsorption and squeeze-out of phosphatidylglycerol from binary phospholipid monolayers containing dipalmitoylphosphatidylcholine. |journal=Biochim. Biophys. Acta |volume=1126 |issue= 1 |pages= 26–34 |year= 1992 |pmid= 1606172 |doi=
*cite journal | author=Weaver TE, Whitsett JA |title=Processing of hydrophobic pulmonary surfactant protein B in rat type II cells. |journal=Am. J. Physiol. |volume=257 |issue= 2 Pt 1 |pages= L100–8 |year= 1989 |pmid= 2475034 |doi=
*cite journal | author=Pilot-Matias TJ, Kister SE, Fox JL, "et al." |title=Structure and organization of the gene encoding human pulmonary surfactant proteolipid SP-B. |journal=DNA |volume=8 |issue= 2 |pages= 75–86 |year= 1989 |pmid= 2924687 |doi=
*cite journal | author=Glasser SW, Korfhagen TR, Weaver T, "et al." |title=cDNA and deduced amino acid sequence of human pulmonary surfactant-associated proteolipid SPL(Phe). |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 12 |pages= 4007–11 |year= 1987 |pmid= 3035561 |doi=
*cite journal | author=Revak SD, Merritt TA, Degryse E, "et al." |title=Use of human surfactant low molecular weight apoproteins in the reconstitution of surfactant biologic activity. |journal=J. Clin. Invest. |volume=81 |issue= 3 |pages= 826–33 |year= 1988 |pmid= 3343343 |doi=
*cite journal | author=Jacobs KA, Phelps DS, Steinbrink R, "et al." |title=Isolation of a cDNA clone encoding a high molecular weight precursor to a 6-kDa pulmonary surfactant-associated protein. |journal=J. Biol. Chem. |volume=262 |issue= 20 |pages= 9808–11 |year= 1987 |pmid= 3597440 |doi=
*cite journal | author=Vamvakopoulos NC, Modi WS, Floros J |title=Mapping the human pulmonary surfactant-associated protein B gene (SFTP3) to chromosome 2p12-->p11.2. |journal=Cytogenet. Cell Genet. |volume=68 |issue= 1-2 |pages= 8–10 |year= 1994 |pmid= 7956367 |doi=
*cite journal | author=Nogee LM, Garnier G, Dietz HC, "et al." |title=A mutation in the surfactant protein B gene responsible for fatal neonatal respiratory disease in multiple kindreds. |journal=J. Clin. Invest. |volume=93 |issue= 4 |pages= 1860–3 |year= 1994 |pmid= 8163685 |doi=
*cite journal | author=Stuhrmann M, Bohnhorst B, Peters U, "et al." |title=Prenatal diagnosis of congenital alveolar proteinosis (surfactant protein B deficiency). |journal=Prenat. Diagn. |volume=18 |issue= 9 |pages= 953–5 |year= 1999 |pmid= 9793979 |doi=
*cite journal | author=Wallot M, Wagenvoort C, deMello D, "et al." |title=Congenital alveolar proteinosis caused by a novel mutation of the surfactant protein B gene and misalignment of lung vessels in consanguineous kindred infants. |journal=Eur. J. Pediatr. |volume=158 |issue= 6 |pages= 513–8 |year= 1999 |pmid= 10378403 |doi=
*cite journal | author=Tredano M, van Elburg RM, Kaspers AG, "et al." |title=Compound SFTPB 1549C-->GAA (121ins2) and 457delC heterozygosity in severe congenital lung disease and surfactant protein B (SP-B) deficiency. |journal=Hum. Mutat. |volume=14 |issue= 6 |pages= 502–9 |year= 2000 |pmid= 10571948 |doi= 10.1002/(SICI)1098-1004(199912)14:6<502::AID-HUMU9>3.0.CO;2-C |doilabel=10.1002/(SICI)1098-1004(199912)14:6502::AID-HUMU93.0.CO;2-C
*cite journal | author=Korimilli A, Gonzales LW, Guttentag SH |title=Intracellular localization of processing events in human surfactant protein B biosynthesis. |journal=J. Biol. Chem. |volume=275 |issue= 12 |pages= 8672–9 |year= 2000 |pmid= 10722708 |doi=
*cite journal | author=Gordon LM, Lee KY, Lipp MM, "et al." |title=Conformational mapping of the N-terminal segment of surfactant protein B in lipid using 13C-enhanced Fourier transform infrared spectroscopy. |journal=J. Pept. Res. |volume=55 |issue= 4 |pages= 330–47 |year= 2000 |pmid= 10798379 |doi=
*cite journal | author=Lin Z, Pearson C, Chinchilli V, "et al." |title=Polymorphisms of human SP-A, SP-B, and SP-D genes: association of SP-B Thr131Ile with ARDS. |journal=Clin. Genet. |volume=58 |issue= 3 |pages= 181–91 |year= 2001 |pmid= 11076040 |doi=
External links
*
PBB_Controls
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