- Complement receptor
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A complement receptor is a receptor of the complement system, a part of the mediated innate immune system. Complement receptors are responsible for detecting pathogens by mechanisms not mediated by antibodies. Complement activity is not antigen sensitive, but can be triggered by specific antigens. Therefore complement (a group of proteins in the serum that help achieve phagocytosis and lysis of antigens) is also part of the humoral immune system.
Contents
Complement receptors
Types include:
CR # Name CD CR1 - CD35 CR2 - CD21 CR3 Macrophage-1 antigen or "integrin alphaMbeta2" CD11b+CD18 CR4 Integrin alphaXbeta2 or "p150,95" CD11c+CD18 - C3a receptor - - C5a receptor CD88 Clinical significance
Defects in these receptors can be associated with disease.[1]
See also
References
External links
Proteins: complement system (C, L, A) Activators/enzymes EarlyMiddleLateInhibitors Complement receptors Membrane-bound_PRRs Cytoplasmic_PRRs Secreted_PRRs Complement receptor · CollectinOther/ungrouped Categories:
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