Glutaryl-CoA dehydrogenase
- Glutaryl-CoA dehydrogenase
protein
Name=glutaryl-Coenzyme A dehydrogenase
caption=
width=
HGNCid=4189
Symbol=GCDH
AltSymbols=
EntrezGene=2639
OMIM=608801
RefSeq=NM_013976
UniProt=Q92947
PDB=
ECnumber=1.3.99.7
Chromosome=19
Arm=p
Band=13.2
LocusSupplementaryData=
Glutaryl-CoA dehydrogenase is an enzyme acting upon glutaryl-coenzyme A, creating crotonyl-coenzyme A.
It plays a role in the metabolism of lysine, hydroxylysine and tryptophan.
Pathology
A defect in this enzyme is associated with neurological condition glutaric acidemia type 1, which is often fatal [The Effect of a Glu370Asp Mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the Dienolate Intermediate] .
References
External links
*
Wikimedia Foundation.
2010.
Look at other dictionaries:
glutaryl-CoA dehydrogenase — glu·ta·ryl CoA de·hy·dro·gen·ase (glooґtə rəl ko aґ de hiґdro jən ās) [EC 1.3.99.7] an enzyme of the oxidoreductase class that catalyzes the oxidative decarboxylation of glutaryl CoA, with sequential reduction of FAD and then… … Medical dictionary
glutaryl-CoA — The mono thiol ester of coenzyme A and glutaric acid; an intermediate in l lysine and l tryptophan catabolism. glutaryl CoA dehydrogenase an enzyme that catalyzes the reaction of glutaryl CoA with an acceptor to form crotonoyl … Medical dictionary
Glutaryl-CoA — Chembox new ImageFile=Glutaryl coenzyme A.svg ImageSize=300px IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=3131 84 8 PubChem=3081383 SMILES= MeSHName=Glutaryl coenzyme+A Section2= Chembox Properties Formula=C26H42N7O19P3S… … Wikipedia
Crotonyl-CoA — Strukturformel Allgemeines Name Crotonyl CoA Summenform … Deutsch Wikipedia
Methylmalonyl-CoA mutase — Rendering based on PDB 2XIJ … Wikipedia
Propionyl-CoA carboxylase — PCCA redirects here. For other uses, see PCCA (disambiguation). Propionyl CoA carboxylase Identifiers EC number 6.4.1.3 CAS number … Wikipedia
Succinate dehydrogenase — (ubiquinone) Subunits: SdhA, SdhB, SdhC and SdhD Identifiers EC number … Wikipedia
Methylcrotonyl-CoA carboxylase — methylcrotonoyl Coenzyme A carboxylase 1 (alpha) Identifiers Symbol MCCC1 Entrez 56922 HUGO … Wikipedia
Methylmalonyl CoA epimerase — Ribbon diagram of methylmalonyl CoA epimerase from Propionibacterium shermanii. From PDB 1JC5 … Wikipedia
Methylglutaconyl-CoA hydratase — AU RNA binding protein/enoyl Coenzyme A hydratase Identifiers Symbol AUH Entrez 549 HUGO … Wikipedia
