Enzyme-linked receptor

Enzyme-linked receptor

An enzyme-linked receptor is a transmembrane receptor, where the binding of an extracellular ligand causes enzymatic activity on the intracellular side.

Examples of the enzymatic activity include:
* Receptor tyrosine kinase, as in fibroblast growth factor receptor. Most enzyme-linked receptors are of this type. [ [http://darwin.nmsu.edu/~molbio/mcb520/lecture10.html lecture10 ] ]
* Serine/threonine-specific protein kinase, as in bone morphogenetic protein
* Guanylate cyclase, as in atrial natriuretic factor receptor

References

External links

* [http://www.scq.ubc.ca/?p=353 Diagram at scq.ubc.ca]


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