Ketazocine

Ketazocine

Chembox new
ImageFile = Ketazocine.svg
ImageSize = 220px
ImageFile2= Ketazocine 3D.png ImageSize2= 200px
IUPACName = (2"R",6"S",11"S")-3-(cyclopropylmethyl)-3,4,5,
6-tetrahydro-8-hydroxy-6,11-dimethyl-2,6-
methano-3-benzazocin-1(2"H")-one
OtherNames =
Section1 = Chembox Identifiers
CASNo = 36292-69-0
PubChem = 71426
SMILES =
MeSHName = ketazocine

Section2 = Chembox Properties
Formula = C18H23NO2
MolarMass = 285.381 g/mol
Appearance =
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Section3 = Chembox Hazards
Solubility =
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Ketazocine (INN) (Ketocyclazocine) is a cyclazocine derivative used in opioid receptor research.Ketocyclazocine is an exogenous (not naturally produced by the body) opioid that binds to the kappa opioid receptor.

Activation of this receptor causes a decrease in pain sensations and increased sleepiness but can also cause psychological symptoms such as feelings of unease, paranoia, and hallucinations. It also causes an increase in urine production because it inhibits the release of vasopressin. (Vasopressin is an endogenous (produced by the body) substance that assists in regulating fluid and electrolyte balance in the body and decreases the amount of water released into the urine.)

Unlike other opioids, substances that only bind to the kappa receptor theoretically do not impair the normal drive to breathe.


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