- CD49b
CD49b (also known as
DX5 ) is anintegrin alpha subunit. It makes up half of the α2β1 integrin duplex.PBB_Summary
section_title =
summary_text = This gene product belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells (the NKT cells), NK cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling. [cite web | title = Entrez Gene: ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3673| accessdate = ]External links
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References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Moroi M, Jung SM |title=Platelet receptors for collagen. |journal=Thromb. Haemost. |volume=78 |issue= 1 |pages= 439–44 |year= 1997 |pmid= 9198193 |doi=
*cite journal | author=Takada Y, Kamata T, Irie A, "et al." |title=Structural basis of integrin-mediated signal transduction. |journal=Matrix Biol. |volume=16 |issue= 4 |pages= 143–51 |year= 1998 |pmid= 9402003 |doi=
*cite journal | author=Dickeson SK, Santoro SA |title=Ligand recognition by the I domain-containing integrins. |journal=Cell. Mol. Life Sci. |volume=54 |issue= 6 |pages= 556–66 |year= 1998 |pmid= 9676575 |doi=
*cite journal | author=Porter JC, Hogg N |title=Integrins take partners: cross-talk between integrins and other membrane receptors. |journal=Trends Cell Biol. |volume=8 |issue= 10 |pages= 390–6 |year= 1999 |pmid= 9789327 |doi=
*cite journal | author=Plenz GA, Deng MC, Robenek H, Völker W |title=Vascular collagens: spotlight on the role of type VIII collagen in atherogenesis. |journal=Atherosclerosis |volume=166 |issue= 1 |pages= 1–11 |year= 2003 |pmid= 12482545 |doi=
*cite journal | author=Charakida M, Tousoulis D, Stefanadis C, Toutouzas P |title=The impact of platelet glycoprotein IIIa and Ia polymorphisms in cardiovascular thrombotic disease. |journal=Italian heart journal : official journal of the Italian Federation of Cardiology |volume=4 |issue= 1 |pages= 17–22 |year= 2003 |pmid= 12690916 |doi=
*cite journal | author=Tsantes AE, Nikolopoulos GK, Bagos PG, "et al." |title=Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and coronary artery disease: a meta-analysis. |journal=Int. J. Cardiol. |volume=118 |issue= 2 |pages= 189–96 |year= 2007 |pmid= 17023078 |doi= 10.1016/j.ijcard.2006.06.047PBB_Controls
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