- CD49c
Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor), also known as ITGA3 and CD49c, is a human
gene .ITGA3 is anintegrin alpha subunit. It makes up half of the α3β1 integrin duplex.PBB_Summary
section_title =
summary_text = ITGA3 encodes the integrin alpha 3 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 ('VLA-3'), very common antigen 2 ('VCA-2'), extracellular matrix receptor 1 ('ECMR1'), and galactoprotein b3 ('GAPB3'). [cite web | title = Entrez Gene: ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3675| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Bosman FT |title=Integrins: cell adhesives and modulators of cell function. |journal=Histochem. J. |volume=25 |issue= 7 |pages= 469–77 |year= 1993 |pmid= 8407358 |doi=
*cite journal | author=Fornaro M, Languino LR |title=Alternatively spliced variants: a new view of the integrin cytoplasmic domain. |journal=Matrix Biol. |volume=16 |issue= 4 |pages= 185–93 |year= 1998 |pmid= 9402008 |doi=External links
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