Diethylthiambutene

Diethylthiambutene

Systematic (IUPAC) name
N,N-diethyl-4,4-dithiophen-2-yl-but-3-en-2-amine
Clinical data
Pregnancy cat.	?
Legal status	Schedule I (US)
Identifiers
CAS number	86-14-6 N
ATC code	None
PubChem	CID 6833
DrugBank	DB01533
ChemSpider	6572 Y
UNII	2Z91X9052O Y
Chemical data
Formula	C16H21NS2
Mol. mass	291.477 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C16H21NS2/c1-4-17(5-2)13(3)12-14(15-8-6-10-18-15)16-9-7-11-19-16/h6-13H,4-5H2,1-3H3 Y Key:CBYWMRHUUVRIAF-UHFFFAOYSA-N Y
Physical data
Melt. point	152–153 °C (306–307 °F)
N(what is this?)  (verify)

Diethylthiambutene (Thiambutene, Themalon, Diethibutin, N,N-Diethyl-1-methyl-3,3-di-2-thienylallylamine) is an opioid analgesic drug developed in the 1950s^[1] which was mainly used as an anesthetic in veterinary medicine and continues, along with the other two thiambutenes dimethylthiambutene and ethylmethylthiambutene to be used for this purpose, particularly in Japan.^[2][3] It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.

References

1. ^ BECKETT AH, CASY AF, HARPER NJ, PHILLIPS PM. Analgesics and their antagonists: some steric and chemical considerations. II. The influence of the basic group on physico-chemical properties and the activity of methadone and thiambutene-type compounds. Journal of Pharmacy and Pharmacology. 1956 Nov;8(11):860-73.
2. ^ Hayes MJ. The use of thiambutene hydrochloride. The Veterinary Record. 1968 Nov 16;83(20):528.
3. ^ Harbison WD, Slocombe RF, Watts SJ, Stewart GA. Thiambutene and acepromazine as analgesic and preanaesthetic agents in horses and sheep. Australian Veterinary Journal. 1974 Dec;50(12):543-6.

This analgesic-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Synthetic opioids Thiophenes Amines Mu-opioid agonists Analgesic stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать курсовую Laura Dutertre Heyday (novel) Look at other dictionaries: diethylthiambutene — noun A particular narcotic painkiller …   Wiktionary Opioid — Endogenous opioid peptides Skeletal molecular images Adrenorphin Amidorphin Casomorphin …   Wikipedia Thiambutene — drugbox IUPAC name = 4,4 dithiophen 2 yl but 3 en 2 amine width = 140 CAS number = ATC prefix = ATC suffix = PubChem = C=12 | H=13 | N=1 | S=2 molecular weight = 235.368 g/mol smiles = s1cccc1C(=CC(N)C)c2sccc2 melting point = 174 melting high =… …   Wikipedia Morphine — This article is about the drug. For other meanings, see Morphine (disambiguation). Morphia redirects here. For other uses, see Morphia (disambiguation). Not to be confused with Morphinae, Morphea, or Morpholine. Morphine …   Wikipedia Opiate — For other uses see Opiate (disambiguation), or for the class of drugs see Opioid. Harvesting the poppy pod. In medicine, the term opiate describes any of the narcotic opioid alkaloids found as natural products in the opium poppy plant …   Wikipedia Phencyclidine — Systematic (IUPAC) name …   Wikipedia Loperamide — Imodium redirects here. For the song by Nirvana, see Breed (song). Loperamide Systematic (IUPAC) name …   Wikipedia Pethidine — Systematic (IUPAC) name …   Wikipedia Opioid receptor — Opioid receptors are a group of G protein coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are 40% identical to somatostatin… …   Wikipedia Oxymorphone — Systematic (IUPAC) name 4,5α epoxy 3,14 dihydroxy 17 methylmorphinan 6 one Clinical data Trade names …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”