Ethylmethylthiambutene

Ethylmethylthiambutene

drugbox
IUPAC_name = N-ethyl-N-methyl-4,4-dithiophen-2-yl-but-3-en-2-amine


width = 140
CAS_number = 441-61-2
ATC_prefix =
ATC_suffix =
PubChem = 197362
smiles = CCN(C)C(C)C=C(c1cccs1)c1cccs1
C=15 | H=19 | N=1 | S=2
molecular_weight = 277.45 g/mol
smiles = CCN(C)C(C)C=C(C1=CC=CS1)C2=CC=CS2
melting_point =
melting_high =
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category =
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legal_CA =
legal_UK =
legal_US = Schedule I
legal_status =
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Ethylmethylthiambutene (N-ethyl-N-methyl-1-methyl-3,3-di-2-thienylallylamine, Emethibutin) is an opioid analgesic drug from the thiambutene family, around 1.3x the potency of morphine. [Adamson DW, Green AF. A new series of analgesics. "Nature". 1950 Jan 21;165(4186):122. PMID 15409854] [Adamson DW, Duffin WM, Green AF. Dithienylbutylamines as analgesics. "Nature". 1951 Jan 27;167(4239):153-4. PMID 14806409] [Green AF. Analgesic and other properties of 3: 3-dithienylalkenylamines. "British Journal of Pharmacology and Chemotherapy". 1953 Mar;8(1):2-9. PMID 13066683] It is under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential.

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