- Glutamyl aminopeptidase
protein
Name=glutamyl aminopeptidase (aminopeptidase A)
caption=
width=
HGNCid=3355
Symbol=ENPEP
AltSymbols=gp160, CD249
EntrezGene=2028
OMIM=138297
RefSeq=NM_001977
UniProt=Q07075
PDB=
ECnumber=3.4.11.7
Chromosome=4
Arm=q
Band=25
LocusSupplementaryData=Glutamyl aminopeptidase also known as aminopeptidase A is an
enzyme encoded by the gene|ENPEPgene . Glutamyl aminopeptidase has also recently been designated CD249 (cluster of differentiation 249).Glutamyl aminopeptidase is a zinc-dependent membrane-bound
aminopeptidase that catalyzes the cleavage of glutamatic and aspartatic amino acid residues from the N-terminus of polypeptides. The enzyme degrades vasoconstrictingangiotensin II into angiotensin III and therefore helps to regulateblood pressure .cite journal | author = Reaux A, Iturrioz X, Vazeux G, Fournie-Zaluski MC, David C, Roques BP, Corvol P, Llorens-Cortes C | title = Aminopeptidase A, which generates one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, has a key role in central control of arterial blood pressure | journal = Biochem. Soc. Trans. | volume = 28 | issue = 4 | pages = 435–40 | year = 2000 | pmid = 10961935 | doi = | issn = ]References
External links
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