Biotin deficiency

Biotin deficiency

Infobox_Disease
Name = PAGENAME


Caption = Biotin
DiseasesDB =
ICD10 = ICD10|E|53|8|e|50
ICD9 = ICD9|266.2
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj = ped
eMedicineTopic = 238
MeshID =

Biotin deficiency is a rare nutritional disorder which can become serious, even fatal, if allowed to progress untreated. It can occur in people of any age, ancestry, or gender.

Biotin deficiency rarely occurs among healthy people, since the daily requirement of biotin is low, many foods provide adequate amounts of it, intestinal bacteria synthesize small amounts of it, and the body effectively scavenges and recycles it from bodily waste. However, deficiencies can be caused by consuming raw egg whites over a period of months to years. Egg whites contain high levels of avidin, a protein that binds biotin strongly. When cooked, avidin is denatured and becomes entirely non-toxic.

ymptoms

Initial symptoms of biotin deficiency include:
#Dry skin
#Seborrheic dermatitis
#Fungal infections
#Rashes including red, patchy ones near the mouth (erythematous periorofacial macular rash)
#Fine and brittle hair
#Hair loss or total baldness (alopecia)

If left untreated, neurological symptoms can develop, including:

#Mild depression, which may progress to profound lassitude and, eventually, to somnolence
#Changes in mental status
#Generalized muscular pains (myalgias)
#Hyperesthesias and paresthesias

Treatment

Biotin deficiency is easily corrected by biotin tablets, which are inexpensive and readily available. If overconsumption of raw egg whites is responsible, a change in diet may be appropriate.

ee also

* Biotinidase deficiency, which is not due to inadequate biotin, but rather to a deficiency in the enzymes which process it.


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Biotin — Biotin[1] …   Wikipedia

  • Biotin — A water soluble B complex vitamin involved in carbon dioxide transfer and therefore essential to the metabolism of carbohydrate and fat. A balanced diet usually contains enough biotin. Foods with high biotin levels include nuts, cereals, green… …   Medical dictionary

  • Biotin — Strukturformel Allgemeines Trivialname Vitamin B7 Vitamin B8 Vitamin H …   Deutsch Wikipedia

  • biotin — /buy euh tin/, n. Biochem. a crystalline, water soluble vitamin, C10H16O3N2S, of the vitamin B complex, that is present in all living cells and functions as a growth factor and as a catalyst in carboxylation reactions. Also called vitamin H.… …   Universalium

  • biotin — n. a vitamin of the B complex that is essential for the metabolism of fat, being involved in fatty acid synthesis and gluconeogenesis. A biotin deficiency is extremely rare in humans; it can be induced by eating large quantities of raw egg white …   The new mediacal dictionary

  • biotin — a B complex vitamin, a deficiency of which in fishes causes convulsions, reduced mucus production and blue slime disease …   Dictionary of ichthyology

  • deficiency — An insufficient quantity of some substance (as in dietary d. or hemoglobin d. in marrow aplasia); organization (as in mental d.); activity (as in enzyme d. or reduced oxygen carrying capacity of the blood), etc., of which the amount present is of …   Medical dictionary

  • Biotinidase deficiency — Infobox Disease Name = PAGENAME Caption = Biotin DiseasesDB = 29822 ICD10 = ICD9 = ICD9|277.6 ICDO = OMIM = 253260 MedlinePlus = eMedicineSubj = ped eMedicineTopic = 239 MeshID = D028921 Biotinidase deficiency is an autosomal recessive metabolic… …   Wikipedia

  • Ornithine transcarbamylase deficiency — Classification and external resources Ornithine ICD 10 E …   Wikipedia

  • Chromium deficiency — Classification and external resources Chromium ICD 10 E61.4 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”