Core enzyme

A core enzyme consists of the subunits of an enzyme that are needed for catalytic activity, as in the core enzyme RNA polymerase.^[1]

An example of a core enzyme is a RNA polymerase enzyme without the sigma factor (σ). This enzyme consists of only two alpha (2α), one beta (β) and one beta prime (β'). This is just one example of a core enzyme. DNA Pol I can also be characterized as having core and holoenzyme segments, where the 5'exonuclease can be removed without destroying enzyme functionality.

References

1. ^ Genetics: Analysis & Principles, 3rd Edition. pp. 811. Brooker, Robert J.

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