CD37

CD37, also known as Cluster of Differentiation 37, is a human gene.cite web | title = Entrez Gene: CD37 CD37 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=951| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.cite web | title = Entrez Gene: CD37 CD37 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=951| accessdate = ]

ee also

* Cluster of differentiation

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Horejsí V, Vlcek C |title=Novel structurally distinct family of leucocyte surface glycoproteins including CD9, CD37, CD53 and CD63. |journal=FEBS Lett. |volume=288 |issue= 1-2 |pages= 1–4 |year= 1991 |pmid= 1879540 |doi=
*cite journal | author=Berditchevski F |title=Complexes of tetraspanins with integrins: more than meets the eye. |journal=J. Cell. Sci. |volume=114 |issue= Pt 23 |pages= 4143–51 |year= 2002 |pmid= 11739647 |doi=
*cite journal | author=Classon BJ, Williams AF, Willis AC, "et al." |title=The primary structure of the human leukocyte antigen CD37, a species homologue of the rat MRC OX-44 antigen. |journal=J. Exp. Med. |volume=172 |issue= 3 |pages= 1007 |year= 1990 |pmid= 2388030 |doi=
*cite journal | author=Classon BJ, Williams AF, Willis AC, "et al." |title=The primary structure of the human leukocyte antigen CD37, a species homologue of the rat MRC OX-44 antigen. |journal=J. Exp. Med. |volume=169 |issue= 4 |pages= 1497–502 |year= 1989 |pmid= 2466944 |doi=
*cite journal | author=Schwartz-Albiez R, Dörken B, Hofmann W, Moldenhauer G |title=The B cell-associated CD37 antigen (gp40-52). Structure and subcellular expression of an extensively glycosylated glycoprotein. |journal=J. Immunol. |volume=140 |issue= 3 |pages= 905–14 |year= 1988 |pmid= 3257508 |doi=
*cite journal | author=Angelisová P, Hilgert I, Horejsí V |title=Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteins. |journal=Immunogenetics |volume=39 |issue= 4 |pages= 249–56 |year= 1994 |pmid= 8119731 |doi=
*cite journal | author=Virtaneva KI, Angelisová P, Baumruker T, "et al." |title=The genes for CD37, CD53, and R2, all members of a novel gene family, are located on different chromosomes. |journal=Immunogenetics |volume=37 |issue= 6 |pages= 461–5 |year= 1993 |pmid= 8436422 |doi=
*cite journal | author=Wright MD, Rochelle JM, Tomlinson MG, "et al." |title=Gene structure, chromosomal localization, and protein sequence of mouse CD53 (Cd53): evidence that the transmembrane 4 superfamily arose by gene duplication. |journal=Int. Immunol. |volume=5 |issue= 2 |pages= 209–16 |year= 1993 |pmid= 8452817 |doi=
*cite journal | author=Serru V, Le Naour F, Billard M, "et al." |title=Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions. |journal=Biochem. J. |volume=340 ( Pt 1) |issue= |pages= 103–11 |year= 1999 |pmid= 10229664 |doi=
*cite journal | author=Okochi H, Mine T, Nashiro K, "et al." |title=Expression of tetraspans transmembrane family in the epithelium of the gastrointestinal tract. |journal=J. Clin. Gastroenterol. |volume=29 |issue= 1 |pages= 63–7 |year= 1999 |pmid= 10405235 |doi=
*cite journal | author=Matsumoto K, Bochner BS, Wakiguchi H, Kurashige T |title=Functional expression of transmembrane 4 superfamily molecules on human eosinophils. |journal=Int. Arch. Allergy Immunol. |volume=120 Suppl 1 |issue= |pages= 38–44 |year= 1999 |pmid= 10529602 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=van Spriel AB, Puls KL, Sofi M, "et al." |title=A regulatory role for CD37 in T cell proliferation. |journal=J. Immunol. |volume=172 |issue= 5 |pages= 2953–61 |year= 2004 |pmid= 14978098 |doi=
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Meyer-Wentrup F, Figdor CG, Ansems M, "et al." |title=Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production. |journal=J. Immunol. |volume=178 |issue= 1 |pages= 154–62 |year= 2007 |pmid= 17182550 |doi=
*cite journal | author=Zhao X, Lapalombella R, Joshi T, "et al." |title=Targeting CD37-positive lymphoid malignancies with a novel engineered small modular immunopharmaceutical. |journal=Blood |volume=110 |issue= 7 |pages= 2569–77 |year= 2007 |pmid= 17440052 |doi= 10.1182/blood-2006-12-062927

External links

*

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