Transcription Factor II F

Transcription Factor II F

protein
Name = general transcription factor IIF, polypeptide 1, 74kDa
caption =


width =
HGNCid = 4652
Symbol = GTF2F1
AltSymbols = TFIIF, BTF4, RAP74
EntrezGene = 2962
OMIM = 189968
RefSeq = NM_002096
UniProt = P35269
PDB =
ECnumber =
Chromosome = 19
Arm = p
Band = 13.3
LocusSupplementaryData = protein
Name = general transcription factor IIF, polypeptide 2, 30kDa
caption =


width =
HGNCid = 4653
Symbol = GTF2F2
AltSymbols = TFIIF, BTF4, RAP30
EntrezGene = 2963
OMIM = 189969
RefSeq = NM_004128
UniProt = P13984
PDB =
ECnumber =
Chromosome = 13
Arm = q
Band = 14
LocusSupplementaryData = protein
Name = general transcription factor IIF, polypeptide 2-like
caption =


width =
HGNCid = 4654
Symbol = GTF2F2L
AltSymbols = TFIIF
EntrezGene = 2964
OMIM =
RefSeq = NG_003013
UniProt =
PDB =
ECnumber =
Chromosome = 4
Arm = q
Band = 31.22
LocusSupplementaryData =

Transcription Factor II F (TFIIF) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.cite book | author = Lewin, Benjamin | title = Genes VIII | publisher = Pearson Prentice Hall | location = Upper Saddle River, NJ | year = 2004 | pages = p636-637 | isbn = 0-13-144946-X | oclc = | doi = ]

Transcription Factor II F is encoded by the gene|GTF2F1, gene|GTF2F2, and gene|GTF2F2L genes.cite journal | author = Finkelstein A, Kostrub CF, Li J, Chavez DP, Wang BQ, Fang SM, Greenblatt J, Burton ZF | title = A cDNA encoding RAP74, a general initiation factor for transcription by RNA polymerase II | journal = Nature | volume = 355 | issue = 6359 | pages = 464–7 | year = 1992 | pmid = 1734284 | doi = 10.1038/355464a0 | issn = ] cite journal | author = Heng HH, Xiao H, Shi XM, Greenblatt J, Tsui LC | title = Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome | journal = Hum. Mol. Genet. | volume = 3 | issue = 1 | pages = 61–4 | year = 1994 | pmid = 8162052 | doi = | issn = ] cite journal | author = Purrello M, Di Pietro C, Rapisarda A, Mirabile E, Motta S, Sichel G, Grzeschik KH | title = Genetic characterization of general transcription factors TFIIF and TFIIB of Homo sapiens sapiens | journal = Cytogenet. Cell Genet. | volume = 69 | issue = 1-2 | pages = 75–80 | year = 1995 | pmid = 7835093 | doi = | issn = ] DNA is thought to be wrapped one complete turn around the preinitiation complex and it is TFIIF that helps keep this tight wrapping.cite journal | author = Lee TI, Young RA | title = Transcription of eukaryotic protein-coding genes | journal = Annu. Rev. Genet. | volume = 34 | issue = | pages = 77–137 | year = 2000 | pmid = 11092823 | doi = 10.1146/annurev.genet.34.1.77] In the process, the torsional strain on the DNA may aid in DNA melting at the promoter, forming the transcription bubble. Of all the general transcription factors, TFIIF is the most similar to bacterial sigma factor.

See also

* TFIIA
* TFIIB
* TFIID
* TFIIE

References

External links

*


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Transcription Factor II B — (TFIIB) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.cite book | author = Lewin, Benjamin | title = Genes VIII | publisher = Pearson Prentice Hall | location = Upper Saddle River, NJ |… …   Wikipedia

  • Transcription Factor II D — (TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.cite book | author = Lewin, Benjamin | title = Genes VIII | publisher = Pearson Prentice Hall | location = Upper Saddle River, NJ |… …   Wikipedia

  • transcription factor — n any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription * * * a protein that regulates gene expression by binding to a DNA sequence adjacent to a sequence encoding a protein or… …   Medical dictionary

  • Transcription factor — In the field of molecular biology, a transcription factor (sometimes called a sequence specific DNA binding factor) is a protein that binds to specific sequences of DNA and thereby controls the transfer (or transcription) of genetic information… …   Wikipedia

  • Transcription Factor II A — protein Name = general transcription factor IIA, 1, 19/37kDa caption = width = HGNCid = 4646 Symbol = GTF2A1 AltSymbols = EntrezGene = 2957 OMIM = 600520 RefSeq = NM 201595 UniProt = P52655 PDB = ECnumber = Chromosome = 14 Arm = q Band = 31… …   Wikipedia

  • Transcription Factor II E — protein Name = general transcription factor IIE, polypeptide 1, alpha 56kDa caption = width = HGNCid = 4650 Symbol = GTF2E1 AltSymbols = TF2E1 EntrezGene = 2960 OMIM = 189962 RefSeq = NM 005513 UniProt = P29083 PDB = ECnumber = Chromosome = 3 Arm …   Wikipedia

  • transcription factor — ▪ biology       molecule that controls the activity of a gene by determining whether the gene s DNA (deoxyribonucleic acid) is transcribed into RNA (ribonucleic acid). The enzyme RNA polymerase catalyzes the chemical reactions that synthesize RNA …   Universalium

  • Transcription Factor II H — protein Name= general transcription factor IIH, polypeptide 1, 62kDa caption= width= HGNCid=4655 Symbol=GTF2H1 AltSymbols= BTF2 EntrezGene=2965 OMIM=189972 RefSeq=NM 005316 UniProt=P32780 PDB= ECnumber= Chromosome=11 Arm=p Band=15.1… …   Wikipedia

  • transcription factor — Protein required for recognition by RNA polymerases of specific stimulatory sequences in eukaryotic genes. Several are known that activate transcription by RNA polymerase II when bound to upstream promoters. Transcription of the 5S RNA gene in… …   Dictionary of molecular biology

  • transcription factor — noun Date: 1972 any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription …   New Collegiate Dictionary

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”