- ITGAE
protein
Name=integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
caption=
width=
HGNCid=6147
Symbol=ITGAE
AltSymbols=CD103, HUMINAE
EntrezGene=3682
OMIM=604682
RefSeq=NM_002208
UniProt=P38570
PDB=
ECnumber=
Chromosome=17
Arm=p
Band=13
LocusSupplementaryData=Integrin, alpha E (ITGAE) also known as CD103 (Cluster of Differentiation 103) is an
integrin .cite journal | author = Kilshaw PJ, Higgins JM | title = Alpha E: no more rejection? | journal = J. Exp. Med. | volume = 196 | issue = 7 | pages = 873–5 | year = 2002 | pmid = 12370249 | doi = 10.1084/jem.20021404 | issn = ] CD103 is expressed on a subset of T cells, termed regulatory T cells (Tregs). Tregs are important for decreasing the immune response and appear to play a crucial role in the prevention of autoimmune diseases. Tregs are defined as CD4+CD25+Foxp3+ cells. Some CD4+FoxP3- cells also express CD103 and have been attributed regulatory activity.ee also
*
Cluster of differentiation References
External links
*
Wikimedia Foundation. 2010.
