Relaxin receptor

Relaxin receptor

protein
Name = relaxin/insulin-like family peptide receptor 1
caption =


width =
HGNCid = 19718
Symbol = RXFP1
AltSymbols = LGR7
EntrezGene = 59350
OMIM = 606654
RefSeq = NM_021634
UniProt = Q9HBX9
PDB =
ECnumber =
Chromosome = 4
Arm = q
Band = 31.3
LocusSupplementaryData =
protein
Name = relaxin/insulin-like family peptide receptor 2
caption =


width =
HGNCid = 17318
Symbol = RXFP2
AltSymbols = LGR8, GREAT, GPR106, INSL3R
EntrezGene = 122042
OMIM = 606655
RefSeq = NM_130806
UniProt = Q8WXD0
PDB =
ECnumber =
Chromosome = 13
Arm = q
Band = 12.3
LocusSupplementaryData =
protein
Name = relaxin/insulin-like family peptide receptor 3
caption =


width =
HGNCid = 24883
Symbol = RXFP3
AltSymbols = RLN3R1, SALPR, GPCR135
EntrezGene = 51289
OMIM = 609445
RefSeq = NM_016568
UniProt = Q9NSD7
PDB =
ECnumber =
Chromosome = 5
Arm = p
Band = 15.1
LocusSupplementaryData = -p14
protein
Name = relaxin/insulin-like family peptide receptor 4
caption =


width =
HGNCid = 14666
Symbol = RXFP4
AltSymbols = GPR100, GPCR142, RLN3R2
EntrezGene = 339403
OMIM = 609043
RefSeq = NM_181885
UniProt = Q8TDU9
PDB =
ECnumber =
Chromosome = 1
Arm = q
Band = 22
LocusSupplementaryData =

The relaxin receptors are a subclass of four closely related G protein-coupled receptors that bind relaxin peptide hormones.cite journal | author = Bathgate RA, Ivell R, Sanborn BM, Sherwood OD, Summers RJ | title = International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides | journal = Pharmacol. Rev. | volume = 58 | issue = 1 | pages = 7–31 | year = 2006 | pmid = 16507880 | doi = 10.1124/pr.58.1.9 | issn = ] cite journal | author = Halls ML, van der Westhuizen ET, Bathgate RA, Summers RJ | title = Relaxin family peptide receptors--former orphans reunite with their parent ligands to activate multiple signalling pathways | journal = Br. J. Pharmacol. | volume = 150 | issue = 6 | pages = 677–91 | year = 2007 | pmid = 17293890 | doi = 10.1038/sj.bjp.0707140 | issn = ]

Below is list of human relaxin receptors, their endogenous peptide hormones, and what down stream enzymes are activated or inhibited by the receptor.

References

External links

* [http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1352 IUPHAR GPCR Database - Relaxin family peptide receptors]
*MeshName|relaxin+receptors


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  • Relaxin/insulin-like family peptide receptor 1 — Relaxin/insulin like family peptide receptor 1, also known as RXFP1, is a human gene.cite web | title = Entrez Gene: RXFP1 relaxin/insulin like family peptide receptor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Relaxin/insulin-like family peptide receptor 2 — Relaxin/insulin like family peptide receptor 2, also known as RXFP2, is a human gene.cite web | title = Entrez Gene: RXFP2 relaxin/insulin like family peptide receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Relaxin/insulin-like family peptide receptor 4 — Relaxin/insulin like family peptide receptor 4, also known as RXFP4, is a human gene.cite web | title = Entrez Gene: RXFP4 relaxin/insulin like family peptide receptor 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Relaxin/insulin-like family peptide receptor 3 — Relaxin/insulin like family peptide receptor 3, also known as RXFP3, is a human gene.cite web | title = Entrez Gene: RXFP3 relaxin/insulin like family peptide receptor 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

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