Lonafarnib

Lonafarnib

Chembox new
ImageFile=Lonafarnib.pngImageSize=200px
IUPACName=4-(2-(4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide
OtherNames=
Section1= Chembox Identifiers
CASNo=
PubChem=148195
SMILES=C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C (C=C(C=C4CCC5=CC(=CN=C35)Br)Cl)Br)C(=O)N

Section2= Chembox Properties
Formula=C27H31Br2ClN4O2
MolarMass=638.82164
Appearance=
Density=
MeltingPt=
BoilingPt=
Solubility=

Section3= Chembox Hazards
MainHazards=
FlashPt=
Autoignition=

Lonafarnib is a farnesyltransferase inhibitor.cite journal |author=Liu G, Marrinan CH, Taylor SA, "et al" |title=Enhancement of the antitumor activity of tamoxifen and anastrozole by the farnesyltransferase inhibitor lonafarnib (SCH66336) |journal=Anticancer Drugs |volume=18 |issue=8 |pages=923–31 |year=2007 |pmid=17667598 |doi=10.1097/CAD.0b013e3280c1416e]

References

ee also

* Laminopathy


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