Small Cajal body specific RNA 20


Small Cajal body specific RNA 20

In molecular biology, Small Cajal body specific RNA 20 (also known as scaRNA20 or ACA66) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA.

scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.cite journal | last = Darzacq | first = X | coauthors = Jady BE, Verheggen C, Kiss AM, Bertrand E, Kiss T | year = 2002 | title = Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs | journal = EMBO J. | volume = 21 | pages = 2746–2756 | pmid = 12032087 | doi = 10.1093/emboj/21.11.2746]

ACA66 (SCARNA20) is a member of the H/ACA box class of snoRNAs that guide the sites of modification of uridines to pseudouridines. This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis cite journal |author= Schattner P, Barberan-Soler S, Lowe TM; |title= A computational screen for mammalian pseudouridylation guide H/ACARNAs. |journal= RNA |volume= 12 |issue= |pages= 15–25 |year= 2006 |pmid=16373490 |doi= 10.1261/rna.2210406] . ACA66 is predicted to guide the pseudouridylation of residue U28 in U12 snRNA cite journal |author= Lestrade L, Weber MJ; |title= snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D boxsnoRNAs. |journal= Nucleic Acids Res |volume= 34 |issue= |pages= D158–D162 |year= 2006 |pmid=16381836 |doi= 10.1093/nar/gkj002] .

References

External links

*
* [http://www-snorna.biotoul.fr/plus.php?id=ACA66 snoRNABase entry for SCARNA20]


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Small Cajal body-specific RNA — Small Cajal body specific RNAs (scaRNAs) are a class of small nucleolar RNAs (snoRNAs) which specifically localise to the Cajal body, a nuclear organelle involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs or snurps). ScaRNAs… …   Wikipedia

  • Small Cajal body specific RNA 6 — (also known as SCARNA6 or U88) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U5 spliceosomal RNA.scaRNAs are a specific class of small nucleolar… …   Wikipedia

  • Small Cajal body specific RNA 23 — (also known as SCARNA23 or ACA11) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U1 spliceosomal RNA.scaRNAs are a specific class of small… …   Wikipedia

  • Small Cajal body specific RNA 15 — (also known as SCARNA15 or ACA45) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U1 spliceosomal RNA.scaRNAs are a specific class of small… …   Wikipedia

  • Small Cajal body specific RNA 16 — (also known as SCARNA16 or ACA47) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U1 spliceosomal RNA.scaRNAs are a specific class of small… …   Wikipedia

  • Small Cajal body specific RNA 24 — (also known as scaRNA24 or ACA12) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U6 spliceosomal RNA.scaRNAs are a specific class of small… …   Wikipedia

  • Small Cajal body specific RNA 8 — (also known as SCARNA8 or U92) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U2 spliceosomal RNA.scaRNAs are a specific class of small nucleolar… …   Wikipedia

  • Small Cajal body-specific RNA 18 — (also known as U91 or U4 8) is a type of small nuclear RNA which localises to the cajal bodies and proposed to guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12cite journal | author = Darzacq X, Jády …   Wikipedia

  • Small Cajal body specific RNA 25 — (otherwise known as scaRNA25, HBI 100, MBI 100 and MBI 114) is a scaRNA which are a class of ncRNAs characterised as a small nuclear RNAs localised to the Cajal bodies [cite journal | last = Darzacq | first = X | coauthors = Jady BE, Verheggen C …   Wikipedia

  • Small Cajal body specific RNA 13 — In molecular biology, Small Cajal body specific RNA 13 (also known as scaRNA13 or U93) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U2 and U5 spliceosomal RNA. scaRNAs are a specific class …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.