Phenotypic switching

Phenotypic switching

Phenotypic switching (a.k.a. phenotypic dimorphism) is switching between two cell-types. An example is Candida albicans, which, when it infects host tissue, switches from the usual unicellular yeast-like form of into an invasive, multicellular filamentous form. [cite journal |author=Kumamoto CA, Vinces MD |title=Contributions of hyphae and hypha-co-regulated genes to Candida albicans virulence |journal=Cell. Microbiol. |volume=7 |issue=11 |pages=1546–54 |year=2005 |pmid=16207242 |doi=10.1111/j.1462-5822.2005.00616.x] This switching between two cell-types is known as dimorphism.

Phenotypic switching in C.albicans include the switch from white cells to opaque cells in need for sexual mating.

References

External links

* [http://www.endocrine-abstracts.org/ea/0002/ea0002p52.htm Endocrine Abstracts] "Are Hox genes responsible for the phenotypic switching and zonation of the adult adrenal cortex?"

* [http://www.jci.org/cgi/content/full/108/11/1577 American Society for Clinical Investigation] "Phenotypic switching in the fungal pathogen Cryptococcus neoformans"

* [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=96790 American Society for Microbiology] "Control of White-Opaque Phenotypic Switching in Candida albicans by the Efg1p Morphogenetic Regulator"

* [http://www.aegis.com/conferences/croi/1997/450.html Conference on Retroviruses and Opportunistic Infections] "Repeated phenotypic switching of HIV-1 in AIDS patients sampled regularly over 2 years."


Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • Candida albicans — Scientific classification Kingdom: Fungi Phylum …   Wikipedia

  • Polyphenism — A polyphenic trait is a trait for which multiple, discrete phenotypes can arise from a single genotype as a result of differing environmental conditions.DefinitionA polyphenism is a biological mechanism that causes a trait to be polyphenic. For… …   Wikipedia

  • Dimorphism — Types of dimorphism (having two body types) include:*Sexual dimorphism, differences in the body appearance of a species based on sex*Nuclear dimorphism, when a cell s nuclear apparatus is composed of two structurally and functionally… …   Wikipedia

  • David R. Soll — Born April 2, 1942 (1942 04 02) (age 69) Philadelphia, Pennsylvania, USA Institutions The University of …   Wikipedia

  • Microorganism — Microbe redirects here. For other uses, see Microbe (disambiguation). A cluster of Escherichia coli …   Wikipedia

  • Ashdown's medium — is a selective culture medium for the isolation and characterisation of Burkholderia pseudomallei (the bacterium that causes melioidosis).Ashdown s medium was first described by LR Ashdown in 1979. [cite journal author=Ashdown LR title=An… …   Wikipedia

  • Archaea — Archea redirects here. For the geologic eon, see Archean. For the spider family, see Archaeidae. Archaea Temporal range: Paleoarchean – Recent Halobacteria sp. strain NRC 1, each cell about 5 μm long …   Wikipedia

  • Mating of yeast — The yeast Saccharomyces cerevisiae is a simple single celled eukaryote with both a diploid and haploid mode of existence. The mating of yeast only occurs between haploids, which can be either the a or α (alpha) mating type and thus display simple …   Wikipedia

  • Trypanosoma brucei — Taxobox color = khaki image width = 240px image caption = Trypanosoma brucei brucei TREU667 (Bloodstream form, phase contrast picture. Black bar indicates 10 µm.) name = Trypanosoma brucei regnum = Protista phylum = Euglenozoa classis =… …   Wikipedia

  • Life Sciences — ▪ 2009 Introduction Zoology       In 2008 several zoological studies provided new insights into how species life history traits (such as the timing of reproduction or the length of life of adult individuals) are derived in part as responses to… …   Universalium

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”