Antagomir

Antagomir

Antagomirs are one of a novel class of chemically engineered oligonucleotides. Antagomirs are used in the silencing of endogenous microRNA. [cite journal |last=Krützfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, Stoffel M. |first= | |year=2005 |month=Dec |title=Silencing of microRNAs in vivo with 'antagomirs' |journal=Nature |volume=438 |issue=7068 |pages=685–9 |pmid=: 16258535 |doi=10.1038/nature04303 ] [cite journal | author=Czech Michael P | title=MicroRNAs as Therapeutic Targets | journal=New England Journal of Medicine | volume=354| issue=11| year=2006| pages=2 | pmid=16540623 | doi=10.1056/NEJMcibr060065 ]

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