FLT1

FLT1

Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), also known as FLT1, is a human gene.

PBB_Summary
section_title =
summary_text = Oncogene FLT belongs to the src gene family and is related to oncogene ROS (MIM 165020). Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The sequence structure of the FLT gene resembles that of the FMS gene (MIM 164770); hence, Yoshida et al. (1987) proposed the name FLT as an acronym for FMS-like tyrosine kinase. [supplied by OMIM] [cite web | title = Entrez Gene: FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2321| accessdate = ]

ee also

* VEGF receptors

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Petrova TV, Makinen T, Alitalo K |title=Signaling via vascular endothelial growth factor receptors. |journal=Exp. Cell Res. |volume=253 |issue= 1 |pages= 117–30 |year= 1999 |pmid= 10579917 |doi= 10.1006/excr.1999.4707
*cite journal | author=Sato Y, Kanno S, Oda N, "et al." |title=Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction. |journal=Ann. N. Y. Acad. Sci. |volume=902 |issue= |pages= 201–5; discussion 205–7 |year= 2000 |pmid= 10865839 |doi=
*cite journal | author=Boyd AW, Lackmann M |title=Signals from Eph and ephrin proteins: a developmental tool kit. |journal=Sci. STKE |volume=2001 |issue= 112 |pages= RE20 |year= 2002 |pmid= 11741094 |doi= 10.1126/stke.2001.112.re20
*cite journal | author=Luttun A, Tjwa M, Carmeliet P |title=Placental growth factor (PlGF) and its receptor Flt-1 (VEGFR-1): novel therapeutic targets for angiogenic disorders. |journal=Ann. N. Y. Acad. Sci. |volume=979 |issue= |pages= 80–93 |year= 2003 |pmid= 12543719 |doi=
*cite journal | author=Maynard SE, Venkatesha S, Thadhani R, Karumanchi SA |title=Soluble Fms-like tyrosine kinase 1 and endothelial dysfunction in the pathogenesis of preeclampsia. |journal=Pediatr. Res. |volume=57 |issue= 5 Pt 2 |pages= 1R–7R |year= 2005 |pmid= 15817508 |doi= 10.1203/01.PDR.0000159567.85157.B7
*cite journal | author=Shibuya M |title=Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis. |journal=Angiogenesis |volume=9 |issue= 4 |pages= 225–30; discussion 231 |year= 2007 |pmid= 17109193 |doi= 10.1007/s10456-006-9055-8
*cite journal | author=Widmer M, Villar J, Benigni A, "et al." |title=Mapping the theories of preeclampsia and the role of angiogenic factors: a systematic review. |journal=Obstetrics and gynecology |volume=109 |issue= 1 |pages= 168–80 |year= 2007 |pmid= 17197602 |doi= 10.1097/01.AOG.0000249609.04831.7c
*cite journal | author=López-Novoa JM |title=Soluble endoglin is an accurate predictor and a pathogenic molecule in pre-eclampsia. |journal=Nephrol. Dial. Transplant. |volume=22 |issue= 3 |pages= 712–4 |year= 2007 |pmid= 17210583 |doi= 10.1093/ndt/gfl768

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