UBE2I

Ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast), also known as UBE2I, is a human gene.

PBB_Summary
section_title =
summary_text = The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [cite web | title = Entrez Gene: UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7329| accessdate = ]

References

PBB_Further_reading
citations =
*cite journal | author=Watanabe TK, Fujiwara T, Kawai A, "et al." |title=Cloning, expression, and mapping of UBE2I, a novel gene encoding a human homologue of yeast ubiquitin-conjugating enzymes which are critical for regulating the cell cycle. |journal=Cytogenet. Cell Genet. |volume=72 |issue= 1 |pages= 86–9 |year= 1996 |pmid= 8565643 |doi=
*cite journal | author=Kovalenko OV, Plug AW, Haaf T, "et al." |title=Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 7 |pages= 2958–63 |year= 1996 |pmid= 8610150 |doi=
*cite journal | author=Jiang W, Koltin Y |title=Two-hybrid interaction of a human UBC9 homolog with centromere proteins of Saccharomyces cerevisiae. |journal=Mol. Gen. Genet. |volume=251 |issue= 2 |pages= 153–60 |year= 1996 |pmid= 8668125 |doi=
*cite journal | author=Yasugi T, Howley PM |title=Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9. |journal=Nucleic Acids Res. |volume=24 |issue= 11 |pages= 2005–10 |year= 1996 |pmid= 8668529 |doi=
*cite journal | author=Göttlicher M, Heck S, Doucas V, "et al." |title=Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor. |journal=Steroids |volume=61 |issue= 4 |pages= 257–62 |year= 1996 |pmid= 8733011 |doi=
*cite journal | author=Schneikert J, Peterziel H, Defossez PA, "et al." |title=Androgen receptor-Ets protein interaction is a novel mechanism for steroid hormone-mediated down-modulation of matrix metalloproteinase expression. |journal=J. Biol. Chem. |volume=271 |issue= 39 |pages= 23907–13 |year= 1996 |pmid= 8798622 |doi=
*cite journal | author=Wang ZY, Qiu QQ, Seufert W, "et al." |title=Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9. |journal=J. Biol. Chem. |volume=271 |issue= 40 |pages= 24811–6 |year= 1996 |pmid= 8798754 |doi=
*cite journal | author=Hateboer G, Hijmans EM, Nooij JB, "et al." |title=mUBC9, a novel adenovirus E1A-interacting protein that complements a yeast cell cycle defect. |journal=J. Biol. Chem. |volume=271 |issue= 42 |pages= 25906–11 |year= 1996 |pmid= 8824223 |doi=
*cite journal | author=Shen Z, Pardington-Purtymun PE, Comeaux JC, "et al." |title=Associations of UBE2I with RAD52, UBL1, p53, and RAD51 proteins in a yeast two-hybrid system. |journal=Genomics |volume=37 |issue= 2 |pages= 183–6 |year= 1997 |pmid= 8921390 |doi= 10.1006/geno.1996.0540
*cite journal | author=Tachibana M, Iwata N, Watanabe A, "et al." |title=Assignment of the gene for a ubiquitin-conjugating enzyme (UBE2I) to human chromosome band 16p13.3 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=75 |issue= 4 |pages= 222–3 |year= 1997 |pmid= 9067428 |doi=
*cite journal | author=Masson M, Menissier-de Murcia J, Mattei MG, "et al." |title=Poly(ADP-ribose) polymerase interacts with a novel human ubiquitin conjugating enzyme: hUbc9. |journal=Gene |volume=190 |issue= 2 |pages= 287–96 |year= 1997 |pmid= 9197546 |doi=
*cite journal | author=Yasugi T, Vidal M, Sakai H, "et al." |title=Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins. |journal=J. Virol. |volume=71 |issue= 8 |pages= 5942–51 |year= 1997 |pmid= 9223484 |doi=
*cite journal | author=Becker K, Schneider P, Hofmann K, "et al." |title=Interaction of Fas(Apo-1/CD95) with proteins implicated in the ubiquitination pathway. |journal=FEBS Lett. |volume=412 |issue= 1 |pages= 102–6 |year= 1997 |pmid= 9257699 |doi=
*cite journal | author=Tong H, Hateboer G, Perrakis A, "et al." |title=Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system. |journal=J. Biol. Chem. |volume=272 |issue= 34 |pages= 21381–7 |year= 1997 |pmid= 9261152 |doi=
*cite journal | author=Hahn SL, Wasylyk B, Criqui-Filipe P, Criqui P |title=Modulation of ETS-1 transcriptional activity by huUBC9, a ubiquitin-conjugating enzyme. |journal=Oncogene |volume=15 |issue= 12 |pages= 1489–95 |year= 1997 |pmid= 9333025 |doi= 10.1038/sj.onc.1201301
*cite journal | author=Hu G, Zhang S, Vidal M, "et al." |title=Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway. |journal=Genes Dev. |volume=11 |issue= 20 |pages= 2701–14 |year= 1997 |pmid= 9334332 |doi=
*cite journal | author=Firestein R, Feuerstein N |title=Association of activating transcription factor 2 (ATF2) with the ubiquitin-conjugating enzyme hUBC9. Implication of the ubiquitin/proteasome pathway in regulation of ATF2 in T cells. |journal=J. Biol. Chem. |volume=273 |issue= 10 |pages= 5892–902 |year= 1998 |pmid= 9488727 |doi=
*cite journal | author=Joanisse DR, Inaguma Y, Tanguay RM |title=Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogaster. |journal=Biochem. Biophys. Res. Commun. |volume=244 |issue= 1 |pages= 102–9 |year= 1998 |pmid= 9514881 |doi= 10.1006/bbrc.1998.8214
*cite journal | author=Saltzman A, Searfoss G, Marcireau C, "et al." |title=hUBC9 associates with MEKK1 and type I TNF-alpha receptor and stimulates NFkappaB activity. |journal=FEBS Lett. |volume=425 |issue= 3 |pages= 431–5 |year= 1998 |pmid= 9563508 |doi=
*cite journal | author=Koldamova RP, Lefterov IM, DiSabella MT, Lazo JS |title=An evolutionarily conserved cysteine protease, human bleomycin hydrolase, binds to the human homologue of ubiquitin-conjugating enzyme 9. |journal=Mol. Pharmacol. |volume=54 |issue= 6 |pages= 954–61 |year= 1999 |pmid= 9855622 |doi=

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