- Lymphotoxin alpha
Lymphotoxin alpha (TNF superfamily, member 1), also known as LTA, is a human
gene .PBB_Summary
section_title =
summary_text = Lymphotoxin alpha, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. LTA is highly inducible, secreted, and exists as homotrimeric molecule. LTA forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. LTA is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. [cite web | title = Entrez Gene: LTA lymphotoxin alpha (TNF superfamily, member 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4049| accessdate = ]ee also
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Lymphotoxin References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Körner H, Sedgwick JD |title=Tumour necrosis factor and lymphotoxin: molecular aspects and role in tissue-specific autoimmunity. |journal=Immunol. Cell Biol. |volume=74 |issue= 5 |pages= 465–72 |year= 1997 |pmid= 8912010 |doi=
*cite journal | author=Wang Q |title=Molecular genetics of coronary artery disease. |journal=Curr. Opin. Cardiol. |volume=20 |issue= 3 |pages= 182–8 |year= 2005 |pmid= 15861005 |doi=
*cite journal | author=Copeland KF |title=Modulation of HIV-1 transcription by cytokines and chemokines. |journal=Mini reviews in medicinal chemistry |volume=5 |issue= 12 |pages= 1093–101 |year= 2006 |pmid= 16375755 |doi=
*cite journal | author=Elewaut D, Ware CF |title=The unconventional role of LT alpha beta in T cell differentiation. |journal=Trends Immunol. |volume=28 |issue= 4 |pages= 169–75 |year= 2007 |pmid= 17336158 |doi= 10.1016/j.it.2007.02.005PBB_Controls
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