Toxic shock syndrome toxin

Toxic shock syndrome toxin

Toxic Shock Syndrome Toxin (TSST) is a superantigen produced by somewhere between 5% and 25% of "Staphylococcus aureus" isolates. It causes toxic shock syndrome by stimulating the release of large amounts of interleukin-1, interleukin-2 and tumour necrosis factor. In general, the toxin is not produced by bacteria growing in the blood; rather, it is produced at the local site of an infection, and then enters the blood stream.

It crosslinks the TCR peptide chain with the peptide chain of the MHC-class II molecule.(DR. Mrugesh K Patel)


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  • Toxic shock syndrome — Infobox Disease DiseasesDB = 13187 ICD10 = ICD10|A|48|3|a|30 ICD9 = ICD9|040.82 ICDO = OMIM = eMedicineSubj = med eMedicineTopic = 2292 eMedicine mult = eMedicine2|emerg|600 eMedicine2|derm|425 eMedicine2|ped|2269 MeshID = D012772 Caption = |… …   Wikipedia

  • toxic shock syndrome — (tok sik) A staphylococcal disease that most commonly affects females who use certain types of tampons during menstruation. It is associated with the production of toxic shock syndrome toxin by certain strains of Staphylococcus aureus …   Dictionary of microbiology

  • toxic shock syndrome — n. a disease, esp. of young menstruating women using highly absorbent tampons, characterized by fever, vomiting, diarrhea, and, often, shock and caused by a toxin releasing bacterium (Staphylococcus aureus) …   English World dictionary

  • toxic shock syndrome — Pathol. a rapidly developing, sometimes fatal infection characterized by sudden onset of fever, gastrointestinal upsets, a sunburnlike rash, and a drop in blood pressure: caused by a Staphylococcus aureus toxin and occurring esp. in menstruating… …   Universalium

  • Toxic shock syndrome — A grave condition occurring predominantly in menstruating women using tampons, toxic shock is characterized by a highly toxic state (with sudden high fever, vomiting, diarrhea, muscle aching) followed by low blood pressure (hypotension) which can …   Medical dictionary

  • toxic shock syndrome — noun Medicine a sometimes fatal syndrome caused by a toxin released by a bacterial infection; most common in women during or immediately after menstruation, and which has been associated with tampon use when the toxin enters the bloodstream… …  

  • toxic shock syndrome — Endotoxic shock caused by bacterial contamination of tampons; toxin responsible is produced by some strains of Staphylococcus aureus …   Dictionary of molecular biology

  • Syndrome, toxic shock — A grave condition occurring predominantly in menstruating women using tampons, toxic shock is characterized by a highly toxic state (with sudden high fever, vomiting, diarrhea, muscle aching) followed by low blood pressure (hypotension) which can …   Medical dictionary

  • Syndrome du choc toxique — CIM 10 : A48.3 Le syndrome du choc toxique (SCT) est une maladie infectieuse rare et aiguë, potentiellement létale, causée par une toxine bactérienne qui pénètre dans la circulation sanguine suite à une infection par un agent pathogène.… …   Wikipédia en Français

  • Toxin — This article is about the class of poisonous substances. For other uses, see Toxin (disambiguation). Universal warning symbol used to indicate toxic substances or environments A toxin (from Ancient Greek: τοξικόν toxikon) is a poisonous… …   Wikipedia

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