FRS2

Fibroblast growth factor receptor substrate 2, also known as FRS2, is a human gene. [cite web | title = Entrez Gene: FRS2 Fibroblast growth factor receptor substrate 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10818| accessdate = ]

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References

Further reading

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*cite journal | author=Wang JK, Xu H, Li HC, Goldfarb M |title=Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras. |journal=Oncogene |volume=13 |issue= 4 |pages= 721–9 |year= 1996 |pmid= 8761293 |doi=
*cite journal | author=Ong SH, Goh KC, Lim YP, "et al." |title=Suc1-associated neurotrophic factor target (SNT) protein is a major FGF-stimulated tyrosine phosphorylated 90-kDa protein which binds to the SH2 domain of GRB2. |journal=Biochem. Biophys. Res. Commun. |volume=225 |issue= 3 |pages= 1021–6 |year= 1996 |pmid= 8780727 |doi= 10.1006/bbrc.1996.1288
*cite journal | author=Kouhara H, Hadari YR, Spivak-Kroizman T, "et al." |title=A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. |journal=Cell |volume=89 |issue= 5 |pages= 693–702 |year= 1997 |pmid= 9182757 |doi=
*cite journal | author=Hadari YR, Kouhara H, Lax I, Schlessinger J |title=Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation. |journal=Mol. Cell. Biol. |volume=18 |issue= 7 |pages= 3966–73 |year= 1998 |pmid= 9632781 |doi=
*cite journal | author=Xu H, Lee KW, Goldfarb M |title=Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins. |journal=J. Biol. Chem. |volume=273 |issue= 29 |pages= 17987–90 |year= 1998 |pmid= 9660748 |doi=
*cite journal | author=Meakin SO, MacDonald JI, Gryz EA, "et al." |title=The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation. |journal=J. Biol. Chem. |volume=274 |issue= 14 |pages= 9861–70 |year= 1999 |pmid= 10092678 |doi=
*cite journal | author=Lim YP, Low BC, Lim J, "et al." |title=Association of atypical protein kinase C isotypes with the docker protein FRS2 in fibroblast growth factor signaling. |journal=J. Biol. Chem. |volume=274 |issue= 27 |pages= 19025–34 |year= 1999 |pmid= 10383403 |doi=
*cite journal | author=Ong SH, Guy GR, Hadari YR, "et al." |title=FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. |journal=Mol. Cell. Biol. |volume=20 |issue= 3 |pages= 979–89 |year= 2000 |pmid= 10629055 |doi=
*cite journal | author=Delahaye L, Rocchi S, Van Obberghen E |title=Potential involvement of FRS2 in insulin signaling. |journal=Endocrinology |volume=141 |issue= 2 |pages= 621–8 |year= 2000 |pmid= 10650943 |doi=
*cite journal | author=Foehr ED, Tatavos A, Tanabe E, "et al." |title=Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors. |journal=FASEB J. |volume=14 |issue= 7 |pages= 973–81 |year= 2000 |pmid= 10783152 |doi=
*cite journal | author=Wang X, Weng LP, Yu Q |title=Specific inhibition of FGF-induced MAPK activation by the receptor-like protein tyrosine phosphatase LAR. |journal=Oncogene |volume=19 |issue= 19 |pages= 2346–53 |year= 2000 |pmid= 10822386 |doi= 10.1038/sj.onc.1203558
*cite journal | author=Dhalluin C, Yan KS, Plotnikova O, "et al." |title=Structural basis of SNT PTB domain interactions with distinct neurotrophic receptors. |journal=Mol. Cell |volume=6 |issue= 4 |pages= 921–9 |year= 2000 |pmid= 11090629 |doi=
*cite journal | author=Kao S, Jaiswal RK, Kolch W, Landreth GE |title=Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells. |journal=J. Biol. Chem. |volume=276 |issue= 21 |pages= 18169–77 |year= 2001 |pmid= 11278445 |doi= 10.1074/jbc.M008870200
*cite journal | author=Ong SH, Hadari YR, Gotoh N, "et al." |title=Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 11 |pages= 6074–9 |year= 2001 |pmid= 11353842 |doi= 10.1073/pnas.111114298
*cite journal | author=Kurokawa K, Iwashita T, Murakami H, "et al." |title=Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction. |journal=Oncogene |volume=20 |issue= 16 |pages= 1929–38 |year= 2001 |pmid= 11360177 |doi= 10.1038/sj.onc.1204290
*cite journal | author=Melillo RM, Santoro M, Ong SH, "et al." |title=Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade. |journal=Mol. Cell. Biol. |volume=21 |issue= 13 |pages= 4177–87 |year= 2001 |pmid= 11390647 |doi= 10.1128/MCB.21.13.4177-4187.2001
*cite journal | author=Hadari YR, Gotoh N, Kouhara H, "et al." |title=Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 15 |pages= 8578–83 |year= 2001 |pmid= 11447289 |doi= 10.1073/pnas.161259898
*cite journal | author=Yan KS, Kuti M, Yan S, "et al." |title=FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors. |journal=J. Biol. Chem. |volume=277 |issue= 19 |pages= 17088–94 |year= 2002 |pmid= 11877385 |doi= 10.1074/jbc.M107963200
*cite journal | author=Wong A, Lamothe B, Lee A, "et al." |title=FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 10 |pages= 6684–9 |year= 2002 |pmid= 11997436 |doi= 10.1073/pnas.052138899
*cite journal | author=Stoletov KV, Ratcliffe KE, Terman BI |title=Fibroblast growth factor receptor substrate 2 participates in vascular endothelial growth factor-induced signaling. |journal=FASEB J. |volume=16 |issue= 10 |pages= 1283–5 |year= 2002 |pmid= 12154000 |doi= 10.1096/fj.01-0835fje

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